Medtronic, DePuy Synthes Shift U.S. Bone Graft Substitute Market Towards Synthetic Demineralized Bone Matrices

Share Article

According to a recent report by iData Research, in 2014, the bone graft substitute market was valued at over $850 million due to the shift towards more expensive demineralized bone matrix and synthetic graft products.

The process of demineralization can make grafts more osteoinductive in exchange for osteoconductivity when compared to allografts and this helps spur the growth of demineralized products.

Vancouver, BC – According to a recently published report by iData Research (, the bone graft substitute market is moving towards synthetics and demineralized bone matrices (DBM) over traditional allograft materials. Because the use of autograft bone requires two incisions and thus an increase in operation time, alternative graft options are often more desirable. The strong market growth in these synthetic materials is partly the result of their improved handling characteristics. In addition, the unit sales growth of complementary orthopedic cell therapy products also acts as a driver for synthetic graft procedure numbers.

“The bone graft substitute market includes many competitors, particularly in the synthetic segment where bone banks are not needed to supply material,” explains Dr. Kamran Zamanian, CEO of iData. “The process of demineralization can make grafts more osteoinductive in exchange for osteoconductivity when compared to allografts and this helps spur the growth of demineralized products.”

Bone grafts are used in a wide range of applications including spinal fusion, trauma, large joint reconstruction, foot reconstruction, as well as oncological and craniomaxillofacial applications.

Other key findings from the 2015 iData Research report series entitled U.S. Market for Orthopedic Biomaterials:

Versatile Delivery Methods
The DBM market is generally considered to be commodity-like. Although the products can be expensive, there is little to differentiate between each brand. That said, value can be added to a product with regards to its carrier packaging and its delivery method. DBMs are available in a range of formulations such as powder, putty, crunch, or as combination bone graft substitute products, providing attractive options to end-users.

Leading Competitors
Medtronic led the bone graft substitute market with nearly 20% market share in 2014 due to their substantial presence in both the demineralized bone graft and synthetic bone graft markets. These products complement those in their spinal fusion department. The company’s leading market share in spinal fusion provides an effective sales channel for their bone graft substitute products.

Other notable competitors in the bone graft substitute market include DePuy Synthes, Stryker, Integra LifeSciences, RTI Surgical, MTF, AlloSource, Baxter, Biomet, Wright Medical, Bacterin International, LifeNet Health, Biocomposites, Exactech, Arthrex, Alphatec Spine, Berkeley Advanced Biomaterials, Etex Corporation, and Osteogenics, among others.

For Further Information
More on the orthopedic bone graft substitute market in the U.S. can be found in the report published by iData entitled U.S. Market for Orthopedic Biomaterials. This report also covers the U.S. market segments for orthopedic bone graft substitutes, orthopedic growth factors, orthopedic stem cell therapy, orthopedic hyaluronic acid viscosupplementations, orthopedic cartilage repairs, and spinal machined bone allografts.

The iData series on the market for orthopedic bone graft substitutes covers the U.S., Japan, South Korea, Australia, China, and 15 countries in Europe. Full reports also provide a comprehensive analysis including units sold, procedure numbers, market value, forecasts, as well as detailed competitive market shares and analysis of major players’ success strategies in each market and segment.

To find out more about U.S. orthopedic biomaterials market data or procedure data, register online or email us at for a U.S. Market for Orthopedic Biomaterials report brochure and synopsis.

About Procedure Tracker
Additional procedure number data is available from iData’s Procedure Tracker service, which allows subscribers to define and analyze procedure data segmented by country, region, hospital, surgery centre, and physician. A customizable dashboard sorts procedure data for further analysis and research.

About iData Research
iData Research ( is an international market research and consulting group focused on providing market intelligence for medical device and pharmaceutical companies. iData covers research in: Spinal Implants and VCF, Spinal MIS, Orthopedic Soft Tissue Repair and Regeneration, Orthopedic Trauma, Large & Small Joints, Anesthesiology, Wound Management, Orthopedics, Cardiovascular, Ophthalmics, Endoscopy, Gynecology, Urology, and more.

Share article on social media or email:

View article via:

Pdf Print

Contact Author

Marvin Cidamon
iData Research
+1 (604) 266-6933 Ext: 205
Email >

Marvin Cidamon
iData Research
604-266-6933 205
Email >
Follow >
iData Research
Like >
iData Research

Follow us on
Visit website