PBS Biotech and RoosterBio Announce Collaboration Agreement to market a line of Mesenchymal Stem/Stromal Cell Bioreactor Expansion Kits

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Collaboration will market a line of Mesenchymal Stem/Stromal Cell Bioreactor Expansion Kits

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PBS Biotech, Inc. and RoosterBio Inc. have announced a commercial collaboration agreement to market a range of easy to use Mesenchymal Stem/Stromal Cell Bioreactor Expansion Kits. The portfolio of kits will facilitate the challenging transition of stem cell culture to more efficient and scalable production platforms. The Start Up Kit will include RoosterBio’s hMSCs and media kits combined with PBS Biotech’s MINI bioreactor and PBS 0.5 liter single-use expansion vessel. A step by step protocol will be included to ensure scientists with little to no experience in bioreactor cell culture can effortlessly generate > 100 million hMSCs within 10 days in the compact, low shear PBS MINI Bioreactor system. Development Kits and Scale Up Kits are also offered, to simplify project-specific optimization and scale up of hMSC production.

The complimentary tools that both RoosterBio and PBS Biotech contribute are intended to address a major bottleneck in the multi-billion dollar Regenerative Medicine industry. Stem cell based technologies are progressing rapidly through the clinic, but manufacturing of cellular therapeutics, including hMSCs, is significantly limited in scale. There are few tools that enable simple and rapid development of scalable production methods of hMSCs.

These new kits are first-in-class products that provide the key elements of scalable stem cell production:

  •     Low shear, easy to use bioreactors
  •     Single-use expansion vessels (500 mL) for rapid and economical process optimization
  •     Well characterized hMSC starting materials
  •     Efficient fed-batch media systems designed for scalability
  •     Microcarriers optimized for hMSC adhesion and 3D expansion

The kit portfolio will enable the rapid development of production methods which can be quickly scaled up, bringing greater efficiencies to the field of Cell Therapy and Regenerative Medicine.

Brian Lee of PBS Biotech, explains “RoosterBio’s robust, well-characterized adult hMSC starting materials and bioreactor-specific media kits have provided consistent, reliable expansion results across a range of PBS Bioreactor working volumes in our lab. We are excited to work with RoosterBio to supply stem cell researchers a stress-free source of cells with minimum start-up time and rapid development efforts.”

Jon Rowley of RoosterBio elaborates “RoosterBio’s in house experience with the gentle mixing and ease of use of the novel PBS MINI bioreactor platform has been very positive. Innovation accelerates when the right groups work in partnership. The launch of this collaboration is an exciting step forward in RoosterBio’s focus to simplify and standardize how stem cells are purchased, expanded, and used in Regenerative Medicine.”

About RoosterBio

RoosterBio is a privately held biofabrication technology and products company focused on accelerating the development of a sustainable regenerative medicine industry, one customer at a time. RoosterBio’s products are high volume, affordable, and well-characterized adult human mesenchymal stem/stromal cells (hMSCs) paired with highly engineered media systems. RoosterBio has simplified and standardized how stem cells are purchased, expanded, and used in development, leading to marked time and costs savings for customers. RoosterBio’s innovative products are ushering in a new era of productivity and standardization into the field, where researchers spend newly found time and money performing more high-value experiments, accelerating the road to discovery in Regenerative Medicine. For more information on RoosterBio and adult stem cells, you can visit http://www.roosterbio.com, follow on twitter (@RoosterBio), or read the blog “Democratizing Cell Technologies” (http://www.roosterbio.blogspot.com).

For more information, please contact us at: info(at)roosterbio.com

About PBS Biotech

PBS Biotech is a privately held company driven to become the leading solution provider of scalable, single use systems for expansion and controlled differentiation of stem cells. PBS Single Use Bioreactors will enable our customers to provide for the millions of patients in need of safe, effective, high value cell based therapies. PBS Vertical-WheelTM technology results in homogenous mixing and reduced shear for uniform suspension of aggregates or micro-carriers. PBS single use bioreactors have working volumes from 100 mL to 500L.

For more information, please visit our website at http://www.pbsbiotech.com or contact us at sales(at)pbsbiotech.com

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Dr. Priya Baraniak
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