New Research Reveals Molecular Differences in Mesothelioma in Men and Women, According to Surviving Mesothelioma

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Scientists hope that understanding how mesothelioma differs between genders and disease subtypes may uncover new ways to treat it.

Mesothelioma Differs Between Men and Women

Gender Differences in Mesothelioma

Insight into the survival advantage of female patients may advance the molecular understanding of malignant pleural mesothelioma...

A new study conducted by doctors at some of the nation’s top cancer centers indicates there are differences at the molecular level in in the tumors of men and women with mesothelioma. Surviving Mesothelioma has just posted an article on the research. Click here to read the full story.

Researchers at Harvard, Baylor and Massachusetts General Hospital analyzed the genomic profiles of ten mesothelioma patients and ten healthy patients. They found that men and women tended to have different kinds of mutated genes.

“Insight into the survival advantage of female patients may advance the molecular understanding of malignant pleural mesothelioma and identify therapeutic interventions that will improve the prognosis for all mesothelioma patients,” says researcher Assunta De Rienzo, PhD, of Brigham and Women’s Hospital.

Just as genetic changes were different between male and female mesothelioma patients, the research team found that they also differ between people with epithelioid and non-epithelioid tumors.

“These are critical findings given that so many of the most promising new treatments for mesothelioma and other cancers are designed to attack these diseases at the molecular level,” says Surviving Mesothelioma’s Managing Editor, Alex Strauss.

To read more about genetic differences in different people with mesothelioma, and how they may impact survival, see Study Finds Molecular and Clinical Gender Differences in Mesothelioma now available on the Surviving Mesothelioma website.

De Rienzo, A, et al, “Gender=Specific Molecular and Clinical Features underlie Malignant Pleural Mesothelioma”, November 10, 2015, Cancer Research, Epub ahead of print,

For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

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Michael Ellis
Cancer Monthy
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