With suicide and the serotonin transporter, SERT, the science shows only a small genetic association while pointing out the politically obvious: the serotonin system is part of every suicide solution.
Chicago, IL (PRWEB) February 21, 2015
“We the People is a higher thought,” opened Bryan W. Brickner, “and the serotonin system is fundamental to all thoughts.”
In We the People and Synaptic Serotonin (5-HT) Science, a new update on the Bryan William Brickner Blog, the focus is serotonergic homeostasis, with particular attention on the central nervous system. In January, Brickner published Shivitti: A Review of Ka-Tzetnik 135633’s Vision, a serotonin system (lysergic acid, LSD) book review on healing Auschwitz nightmares. Today’s post continues the serotonin and healing – for all people – storyline with new 2015 science from the National Institutes of Health (PubMed), which highlights: selective serotonin reuptake inhibitors (SSRIs) and obsessive-compulsive disorder (OCD), 5-HT3 receptors and OCD, prefrontal cortex (brain) and 5-HT2A receptors, and genetic research on suicide and the serotonin transporter gene (5-HTT, SERT).
“There are two today on OCD,” explained Brickner, “with one on the robust data supporting the effectiveness of treatment with selective serotonin reuptake inhibitors (SSRIs), the acknowledged first-line pharmacological treatment of choice.”
“The second OCD serotonin report is scanty,” Brickner continued, “as the research is hampered by a lack of data; the scientific interest is in the serotonin 5-HT3 receptor and OCD patients – though a PubMed review only turned up six publications on the topic, not enough to draw valid conclusions.”
“For the brain serotonin science,” noted Brickner, “research shows the 5-HT2A receptors in the prefrontal cortex regulating dopamine release; this stimulates a ‘long-loop’ feedback system from the cortex to other parts of the brain … and back.”
“With suicide and the serotonin transporter, SERT,” Brickner closed, “the science shows only a small genetic association while pointing out the politically obvious: the serotonin system is part of every suicide solution.”
Brickner has a 1997 political science doctorate from Purdue University and is the author of several political theory books, to include: The Promise Keepers: Politics and Promises (1999), Article the first of the Bill of Rights (2006), and Shivitti: A Review of Ka-Tzetnik 135633’s Vision (2015). He also writes political fiction, such as the novella thereafter (2013), and is the publisher of The Cannabis Papers: A citizen’s guide to cannabinoids (2011) and The Bryan William Brickner Blog, a resource for the political science of constitutions and the biological science of receptors.
Next Ew Publishing: Tomorrow, Sunday 22 February, We the People, Publius and Homeostatic Cannabinoids.