Desferal significantly decreased peritoneal fibrosis, iron deposition and nuclear 8-hydroxy-2'-deoxyguanosine [indicator of oxidative stress] levels in mesothelial cells.
Raleigh, NC (PRWEB) April 22, 2016
New research conducted in Nagoya, Japan suggests that reducing iron overload after asbestos exposure could reduce the chance of developing malignant mesothelioma. Surviving Mesothelioma has just posted an article on the new study. Click here to read it now.
In their search for a mesothelioma prevention strategy, ivestigators at Nagoya University Graduate School of Medicine used a chelating drug (desferal) to reduce the amount of iron in the bodies of lab rats with asbestos-induced pre-cancerous changes.
“Desferal significantly decreased peritoneal fibrosis, iron deposition and nuclear 8-hydroxy-2'-deoxyguanosine [indicator of oxidative stress] levels in mesothelial cells,” reports study author Dr. Jiang Li in the journal Cancer Science.
In other words, iron removal scaled back several of the processes that can give rise to mesothelioma cancer even decades after asbestos exposure.
“This research could be critical for the tens of thousands of people who were negligently exposed to asbestos,” says Alex Strauss, Managing Editor of Surviving Mesothelioma. “For now, there is no know way to prevent development of the disease. All they can do is wait and hope.”
To read more about the possible link between iron and mesothelioma development, see Iron Removal May Reduce Mesothelioma Risk After Asbestos Exposure, now available on the Surviving Mesothelioma website.
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