Chinese Study Finds Drug Made From Frog Eggs May Shrink Mesothelioma Tumors, According to Surviving Mesothelioma

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Doctors say a drug derived from the eggs of the leopard frog and a malaria drug may offer a powerful new mesothelioma treatment combination.

Tree Frog Derivative for Mesothelioma Treatment

New Drug Combination for Mesothelioma

Both in vitro and in vivo Isobologram analyses showed synergistic effects on the proliferation of NSCLC cells under the treatment with Onc and DHA.

Cancer researchers in Shanghai, China have recently tested what they say may be a novel treatment approach for malignant mesothelioma. Surviving Mesothelioma has just posted an article on the study. Click here to read it now.

Scientists at Tongji University combined Onconase, an enzyme derived from the eggs and embryos of the leopard frog, with the malaria drug dihydroartemisinin (DHA) and applied it to non-small cell lung cancer and malignant mesothelioma cells. The results were encouraging.

“Both in vitro and in vivo Isobologram analyses showed synergistic effects on the proliferation of NSCLC cells under the treatment with Onc and DHA,” writes Dr. Ruling Shen with the School of Life Science and Technology at Tongji University.

According to the report, the results were also good when the combination was given to mice who were infected with lung cancer or malignant mesothelioma.

“We are encouraged by the promise of the Onc/DHA study and look forward to hearing more about this potential new mesothelioma treatment approach as more studies are conducted,” says Alex Strauss, Managing Editor of Surviving Mesothelioma. “We will follow the progress of this drug and continue to keep our readers informed.”

For more information on the results of the new mesothelioma drug study, as well as how it is believed to work, see New Drug Combination May Extend Mesothelioma Survival, now available on the Surviving Mesothelioma website.

Shen, R et al, “Combination of onconase and dihydroartemisinin synergistically suppresses growth and angiogenesis of non-small cell lung carcinoma and malignant mesothelioma”, September 2, 2016, Acta Biochimica et Biophysica Sinica, Epub ahead of print, http://abbs.oxfordjournals.org/content/early/2016/09/02/abbs.gmw082

For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

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Cancer Monthy
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