CHICAGO (PRWEB) November 28, 2016
The impact of pressure in breast compression on screening performance was the focus of research accepted for presentation here at the 102nd Annual Radiological Society of North America (RSNA) meeting, November 27-December 2, 2016. It appears that Sigmascreening’s Sensitive Sigma Paddle, with its intermediate target pressure, could also improve detection rates.
Results from an earlier study (“Performance of breast screening and cancer detection depends on mammography compression,” published in June 2016 in Breast Imaging (DOI: 10.1007/978-3-319-41546-8_24)), demonstrated that compression pressures in lower ranges lead to a higher recall rate and a higher false positives fraction and compression pressures in the higher ranges reduce detectability of breast cancer.
An important follow up of this study will be presented by Nico Karssemeijer, PhD, Nijmegen, Netherlands at the RSNA: “High Breast Compression in Mammography May Reduce Sensitivity,” (RC215-08), Monday, Nov. 28 10:10AM - 10:20AM in the Arie Crown Theater.
The aim of this study was to determine breast cancer screening outcomes in relation to the compression pressure applied during mammography. After adjusting for confounders, results demonstrate that a pressure around 75 mmHg (+/-5 mmHg) showed the best breast cancer detection rate and the best positive predictive value when compared to lower and higher compression groups. Program sensitivity decreased with increasing pressure, resulting in a higher interval cancer rate in the group with the highest compression pressure. The authors concluded that, if too much or too little pressure is applied, this may increase the number of interval cancers and decrease the PPV. These data support the introduction and use of pressure guided compression.
Sigmascreening is a medical device company focusing on the development of new innovative products in the area of digital mammography and breast cancer screening. The Sensitive Sigma Paddle is our CE-certified product, based on our patented technology preventing over- and under-compression. We aim to introduce new products that will improve mammography and contribute to the early detection of cancer which ultimately can save lives.