New Research Unlocks Some of the Mystery Behind Mesothelioma Development, According to Surviving Mesothelioma

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Researchers in Japan say changes to the T-cells in asbestos exposed people may help explain why some develop malignant mesothelioma.

Mesothelioma Results from Immune Disfunction

T-Cells Changes Triggered by Asbestos

The overall findings indicate that antitumor immunity in asbestos-exposed individuals may be reduced...

Scientists at Okayama, Japan tested the immune system cells of people with asbestos-related conditions like mesothelioma and found a definite difference from the cells of healthy people. Surviving Mesothelioma has published an article on the new research. Click here to read it now.

Using blood samples from healthy people and those with conditions such as pleural mesothelioma, doctors at Kawasaki Medical School and Okayama University found that asbestos had made significant changes to the immune systems of the sick patients.

“The overall findings indicate that antitumor immunity in asbestos-exposed individuals may be reduced...through changes in the function and volume of regulatory T-cells,” writes study author Dr. Suni Lee of Kawasaki University.

Writing in the International Journal of Oncology, Dr. Lee and colleagues say exposing T-cells to asbestos directly also triggered changes that could explain why some people develop mesothelioma after asbestos exposure.

“Understanding the reasons behind immune system deactivation in mesothelioma patients is an essential step toward developing treatments to counteract this deactivation with immunotherapy,” says Alex Strauss, Managing Editor of Surviving Mesothelioma.

To read more about the immune system’s response to asbestos exposure, see Asbestos-Related T-Cell Changes Help Explain Mesothelioma Development, now available on the Surviving Mesothelioma website.

Lee, S, et al, “accelerated cell cycle progression of human regulatory T cell-like cell line caused by continuous exposure to asbestos fibers,” November 2016, International Journal of Oncology, Epub ahead of print, https://www.researchgate.net/publication/310733102

For nearly ten years, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

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