Article Highlights Importance of Careful Patient Selection in Mesothelioma Immunotherapy Treatment, According to Surviving Mesothelioma

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Researchers with a company that makes antibody-based immunotherapy drugs are calling for the development of new patient selection strategies for people with malignant mesothelioma and other intractable cancers.

Treating Mesothelioma with Antibody Drug Conjugates

Antibody Drug Conjugates for Mesothelioma

...patient selection strategy linked to target expression on the tumor is thus critically important...

The authors of a new article on antibody-drug conjugates (ADCs) say these drugs are most helpful for people who meet certain criteria. Surviving Mesothelioma has more on what that news may mean for mesothelioma patients. Click here to read it now.

In an article in Advances in Therapy, John Lambert and Charles Morris of Massachusetts-based ImmunoGen say the effectiveness of ADCs is largely dependent on how much of the target molecule a patient’s cancer cells produce.

“The development of a patient selection strategy linked to target expression on the tumor is thus critically important for identifying the population appropriate for receiving treatment,” the two conclude.

“Although an ADC like anetumab ravtansine appears to offer new hope for mesothelioma treatment, this article reminds us that these drugs are only effective in the right patients and may be a waste of time and resources for others,” says Alex Strauss, Managing Editor for Surviving Mesothelioma.

To read more about the article, ADCs, and the investigational drug anetumab ravtansine, see The Key to Mesothelioma Treatment Success with Immunotherapy now available on the Surviving Mesothelioma website.

Lambert, JM and Morris, CQ, “Antibody-drug conjugates (ADCs) for personalized treatment of solid tumors: A review”, March 30, 2017, Advances in Therapy, Epub ahead of print,

For more than a decade, Surviving Mesothelioma has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

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Michael Ellis
Cancer Monthy
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