Cost-Efficient and Green Manufacturing of Peptides Thanks to Molecular Hiving Technology, Upcoming Webinar Hosted by Xtalks

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In this free webinar, the featured speaker will explain how to synthesize peptides by Molecular Hiving™ technology. Attendees will learn of the advantages and the environmental benefits of Molecular Hiving™ technology, as well as the manufacture of peptides without CMR solvents and reagents.

Xtalks Life Science Webinars

Join industry expert Dr. Wolfgang Seufert, Director Production III – Process Development, Bachem in a live session on Tuesday, July 7, 2020 at 10am EDT (3pm BST/UK, 4pm CEST, 11pm JST/Japan).

Bachem and Jitsubo CO., LTD. recently announced the signature of an exclusive Licensing Agreement for Jitsubo’s Molecular Hiving™ technology. Under the License agreement, Jitsubo will develop selected manufacturing processes using their Molecular Hiving technology™ and transfer these processes to Bachem. Bachem will further optimize, scale up and produce for commercial applications.

Molecular Hiving is a tag-assisted liquid-phase peptide synthesis technology developed by Professor Kazuhiro Chiba at Tokyo University of Technology and Agriculture. This technology uses a hydrophobic tag, which is applied in the same way as the resin for solid-phase peptide synthesis (SPPS) processes.

The same standard Fmoc amino acid derivatives as for SPPS are applied for assembling the peptide chain. However, all couplings and cleavages of the Fmoc protecting group are performed in solution allowing for fast reactions and direct in-process controls, e.g. by HPLC. Excess reagents as well as coupling and cleavage related by-products are solely removed by aqueous extractions. Therefore, intermediate isolation of the tag-bound peptide and excessive washing steps are not required for Molecular Hiving™ technology.

In this webinar, the speaker will guide attendees through the individual steps for synthesis of peptides applying Molecular Hiving™ technology. Webinar attendees will learn about the scalability and the substantial advantages of this technology regarding efficiency and towards greener manufacturing, as solvent consumption and material requirements are significantly reduced compared to conventional SPPS processes. Molecular Hiving™ also allows the synthesis of peptides without the use of solvents and reagents which are carcinogenic, mutagenic, or toxic to reproduction (CMR substances).

For more information or to register for this event, visit Cost-Efficient and Green Manufacturing of Peptides Thanks to Molecular Hiving Technology.


Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

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Sydney Perelmutter
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