Dallas, Texas (PRWEB) September 21, 2014
Originally approved by the Food and Drug Administration (FDA) in 1996, GSK’s Flovent (fluticasone propionate) is a synthetic ICS therapy with potent anti-inflammatory activity. It is used for the maintenance treatment of asthma prophylactically in children and adults. Flovent is now available in two formulations, Diskus and HFA, which received the FDA approval in 2000 and 2004, respectively. Flovent’s active ingredient, fluticasone propionate, can bind to glucocorticoid receptors with high affinity and inhibit the secretion of mediators involved in asthma, such as histamine, eicosanoids, leukotrienes, and cytokines. It is three times more potent than budenoside, and two times more potent than the active metabolite of beclomethasone dipropionate.
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The asthma market saw very slow growth over the past decade, as it has become saturated with relatively efficacious standard therapies, such as short-acting beta-agonists (SABAs), inhaled corticosteroids (ICSs), inhaled corticosteroids and long-acting beta-agonists (ICS/LABAs), and leukotriene modifiers, and has also been facing increasing generic competition. However, the launch of seven novel targeted biologic agents and once-daily ICS and ICS/LABA therapies delivered by the next-generation inhalers will strongly drive the market growth over the next 10 years. The biologic agents will not only reshape the market growth, but will also mark the beginning of a new era of a personalized approach to asthma treatment. The realization that asthma is a very heterogeneous disease is highly reflected in the rich assortment of these targeted therapies in the late-stage pipeline.
- Overview of Asthma, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
- Detailed information on Flovent including product description, safety and efficacy profiles as well as a SWOT analysis.
- Sales forecast for Flovent for the top eight countries from 2013 to 2023.
- Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan and Australia.
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- Make more informed business decisions from insightful and in-depth analysis of Flovent performance
- Obtain sales forecast for Flovent from 2013-2023 in top eight countries (the US, France, Germany, Italy, Spain, the UK, Japan and Australia)
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Table of Contents
1 Table of Contents
1.1 List of Tables
1.2 List of Figures
2.2 Related Reports
2.3 Upcoming Related Reports
3 Disease Overview
3.1 Etiology and Pathophysiology
3.1.4 Quality of Life
4 Disease Management
4.1 Diagnosis and Treatment Overview
4.1.2 Treatment Guidelines, Clinical Practice, and Leading Prescribed Drugs
4.1.3 Clinical Practice
5 Competitive Assessment
5.2 Strategic Competitor Assessment
6 Flovent (fluticasone propionate)
6.4 SWOT Analysis
7.4 Forecasting Methodology
7.4.1 Diagnosed Asthma Patients
7.4.2 Percent Drug-Treated Patients
7.4.3 General Pricing Assumptions
7.4.4 Individual Drug Assumptions
7.4.5 Generic Erosion
7.5 Physicians and Specialists Included in This Study
7.6 About the Authors
7.6.4 Global Head of Healthcare
7.7 About GlobalData
List of Tables
Table 1: Symptoms of Asthma
Table 2: Treatment Guidelines for Asthma by Country
Table 3: Most Prescribed Drugs for Asthma by Class and Disease Severity in the Global Markets, 2013
Table 4: Dosing of Common ICSs for Adult Asthma Therapy to Achieve Equivalent Therapeutic Potency
Table 5: Recommended Low Daily Dose of ICSs in Children with Asthma Under Five Years of Age
Table 6: Leading Treatments for Asthma, 2014
Table 7: Product Profile - Flovent
Table 8: Efficacy - Flovent Diskus Versus Placebo
Table 9: Adverse Events Related to Flovent Diskus
Table 10: Flovent SWOT Analysis, 2014
Table 11: Global Sales Forecast ($) for Flovent, 2013-2023
Table 12: High-Prescribing Physicians (non-KOLs) Surveyed, By Country
List of Figures
Figure 1:Stepwise Disease Management Approach for Asthma in Adults
Figure 2: Stepwise Disease Management Approach for Asthma in Children Age Five and Younger
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