YORBA LINDA, Calif. (PRWEB) September 14, 2018
Recent advances in phage display for molecular evolution incorporate deep sequencing to enable greater library coverage. However, severe gaps and limitations associated with next-generation sequencing (NGS) library construction and biophysical follow-up of potential hits remain.
Multiplexed phage display provides a simple, robust, and seamless high-throughput-ready version of phage display that can simultaneously screen and bioinformatically analyze up to 96 peptide phage libraries in parallel.
As a case study, raising peptide binders against the low-density lipoprotein receptor-related protein 6 (LRP6) using MPD generated more detailed results in a shorter time than standard phage display methods. To accommodate the large number of potential lead peptides from the screening, the ForteBio Octet system was used to characterize streptavidin peptide fusions generated by in vitro translation.
In this webinar, which is sponsored by ForteBio LLC, attendees will learn to use next-generation sequencing for phage display. They will also understand how to generate streptavidin peptide fusions quickly and inexpensively.
The speaker for this event will be Dr. Thomas Hengstl, a software product manager with Molecular Devices.
Hengstl is currently a product manager for software and compliance with Molecular Devices. Prior to joining the company, he received his doctorate in biophysics and biochemistry through a joint international, industrial program between the University of Natural Sciences Salzburg and Genentech Inc. The development of the multiplexed phage display workflow described in the webinar was a product of his doctorate program.
LabRoot will host the webinar September 27, 2018, beginning at 8 a.m. PDT. To learn more about this event, discover the continuing education credits available, or to register for free, click here.
About Pall ForteBio
Pall ForteBio is a division of Pall Life Sciences that provides analytical systems to accelerate biotherapeutic drug discovery and development. These systems facilitate real-time, label-free analysis of biomolecular interactions, providing information on affinity, kinetics and concentration. Pall ForteBio's analytical solutions enable more efficient and accurate characterization of drug candidates, delivering greater value to the drug discovery and development markets.
For more information, visit http://www.fortebio.com.
LabRoots is the leading scientific social networking website, which provides daily scientific trending news and science-themed apparel, as well as produces educational virtual events and webinars, on the latest discoveries and advancements in science. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.