Huntington Beach Dentist Dr. Rassouli Comments on the New Study on the Link between Genetic Defects in Tooth Enamel and Dental Caries

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Dr. Rassouli has commented on the newly suspected link between genetic defects in tooth enamel and dental carries.

Dr. A. Rassouli, Dentist Huntington Beach

Dr. A. Rassouli

Dr. Rassouli, a dentist in Huntington Beach, comments on the new study linking genetic defects in dental enamel with caries. Tooth decay is caused by the oral bacteria that live in plaque, but while poor dental hygiene is a major contributor to cavities, bacteria can also occur in people who practice good dental hygiene. Researchers recently focused their efforts on why some people with excellent dental habits develop cavities, while others with less careful habits do not.

Researchers from the Centre of Dental Medicine and the Institute of Molecular Life Sciences at the University of Zurich found that genetic mutations altered the way enamel developed. These mutations in the Wnt signaling pathway also play a role in the development of cancer and some other physical defects. The Wnt signaling pathway affects the way enamel proteins develop. In the study, which is described by, every mouse with a defect in the Wnt signaling pathway had tooth decay.

Wnt signaling pathway defects were found to alter to hardness and composition of dental enamel, making it more easily penetrated by bacteria and acids. This leads to tooth decay even in those who maintain good dental hygiene. While more research is needed to better understand the nature of the defect, this study lays the groundwork for the development of new products to prevent tooth decay in those with weak or defective enamel.

The right preventive dental care, such as fluoride treatments and dental sealants, can help reduce the risk of decay even in those who are vulnerable. Dr. Rassouli also offers a wide range of treatment options, including:

  •     Orthodontics, including Invisalign
  •     Same day dentistry
  •     Tooth whitening treatments
  •     Tooth-colored fillings
  •     Dental implants
  •     Oral surgery
  •     Pinhole surgery
  •     TMJ treatments
  •     Sleep apnea treatments
  •     Porcelain veneers

About Dr. Rassouli

Dr. Rassouli is a graduate of the University of Southern California and the co-founder of the South Coast Dental Academy. He served on USC’s prestigious Century Club and the Accreditation Committee, and has been recognized for his commitment to continuing education.


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Kevin Neman
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