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ISPE Names Takeda the 2022 Facility of the Year Awards Overall Winner
  • USA - English


News provided by

ISPE

Nov 01, 2022, 19:00 ET

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The International Society for Pharmaceutical Engineering (ISPE) has announced Takeda Pharmaceuticals International AG as the 2022 Facility of the Year Awards (FOYA) Overall Winner for their project TaSiVa located in Singen, Germany at the 2022 Membership Awards and Lunch during the 2022 ISPE Annual Meeting & Expo.

NORTH BETHESDA, Md., Nov. 1, 2022 /PRNewswire-PRWeb/ -- The International Society for Pharmaceutical Engineering (ISPE) has announced Takeda Pharmaceuticals International AG as the 2022 Facility of the Year Awards (FOYA) Overall Winner for their project TaSiVa in Singen, Germany at the 2022 Membership Awards and Lunch during the 2022 ISPE Annual Meeting & Expo.

Takeda Pharmaceuticals International AG was awarded the 2022 FOYA Pharma 4.0™ Category Award in April 2022 for its TaSiVa Facility in Singen, Germany for its dengue vaccine candidate. Vaccines represent one of Takeda's core therapeutic areas. This project has provided capacity for almost 40 million vaccines annually while modernizing the site into a highly automated digital pharmaceutical facility.

From the beginning of the project, the team introduced digital solutions to identify innovative Pharma 4.0™ technologies which would support the delivery of the project by increasing productivity, quality, and efficiency of processes within the plant. They also conducted a significant IT infrastructure upgrade to ensure that the facility was fit to operate as a highly automated facility.

Takeda's digital vision and strategy also included applying artificial intelligence and machine learning in several areas. An advanced algorithm was developed to select bags of drug substances for formulation based on a targeted potency model. The manual process of quantifying immune-stained foci for potency assay was converted to an automated system that could be initially trained using thousands of pictures and is targeted for fully automated counting in routine operations. AI-enabled, automated visual inspection lyophilized product was developed with high accuracy and low false reject rates.

The project also implemented robotics where appropriate to improve efficiencies and reduce safety and ergonomic risks. Two collaborative robots were installed to load syringes and vials onto the packaging lines and can work adjacent to the operators.    

The Takeda TaSiVa project exemplifies how the application of innovation in advanced digital technologies led to improved outcomes in terms of safety, product quality, and productivity in a modern, pharmaceutical manufacturing facility using Pharma 4.0™ technologies.

For more information on Takeda's award-winning biomanufacturing facility and the FOYA program, please visit ISPE.org/FOYA for more information.

About the ISPE Facility of the Year Awards Program
Established in 2005, The Facility of the Year Awards (FOYA) recognizes state-of-the-art projects utilizing new, innovative technologies to improve the quality of products, reduce the cost of producing high-quality medicines, and demonstrate advances in project delivery. The FOYA program provides a platform for the pharmaceutical science and manufacturing industry to showcase its accomplishments in facility design, construction, and operation while sharing the development of new technology applications and cutting-edge approaches. Visit ISPE.org/FOYA for more information.

About ISPE
The International Society for Pharmaceutical Engineering (ISPE) is a nonprofit association serving its members through leading scientific, technical, and regulatory advancement across the entire pharmaceutical lifecycle. The 20,000 members of ISPE are building solutions in the development and manufacture of safe, effective pharmaceutical and biologic medicines, and medical delivery devices in more than 90 countries around the world. Founded in 1980, ISPE has its worldwide headquarters and training center in North Bethesda, Maryland, USA, and its operations center in Tampa, Florida, USA. Visit ISPE.org for more information

Media Contact

Kristin LeMunyon, ISPE, 813-960-2105, [email protected]

SOURCE ISPE

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