RSSearch® Patient Registry Surpasses 25,000 Patient Cases Using Stereotactic Body Radiotherapy/Stereotactic Radiosurgery

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The RSSearch Registry – led by the Radiosurgery Society – is the largest and most robust live database of its kind in the field of SRS/SBRT.

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"The RSSearch Registry is a gold mine of data, diligently gathered by dedicated providers across the globe, to provide valuable insight into real-world outcomes of SRS/SBRT treatments. This is exemplified by the significant outcome studies published from this data," stated Anand Mahadevan, MD.

The Radiosurgery Society (RSS), a non-profit organization of medical professionals dedicated to advancing the science and clinical practice of stereotactic body radiotherapy (SBRT) and radiosurgery (SRS), announced today that its RSSearch® Patient Registry has surpassed 25,000 patient cases treated with SRS/SBRT. The breadth of patient data entered into the multi-institutional registry makes it by far the largest and most robust live database of its kind in the field of SRS/SBRT managed by a professional medical society.

“The RSSearch Registry is a gold mine of data, diligently gathered by dedicated providers across the globe, to provide valuable insight into real-world outcomes of SRS/SBRT treatments. This is exemplified by the significant outcome studies published from this data. For instance, our paper “Stereotactic Body Radiotherapy for Liver Metastasis” has been reported as one of the top 3 most cited articles by the Journal of Radiation Oncology since 2018, providing useful data for patients and providers on the usefulness of SBRT in difficult situations,” stated Anand Mahadevan, MD, Professor and Chairman, Radiation Oncology at Geisinger Health, Geisinger Cancer Institute, Danville, PA.

The RSSearch Patient Registry is an observational registry established to standardize data collection from patients treated with SRS/SBRT. It was initially conceptualized and designed in 2005 by a Clinical Advisory Board comprised of radiation oncologists, neurosurgeons, medical oncologists and medical physicists to provide a method to collect standardized data on the use of SRS/SBRT treatment practices and outcomes to help determine the most effective clinical use of SRS/SBRT.

“Having a comprehensive resource such as RSSearch, which includes both clinical and radiation planning data points has enabled our faculty and residents work on several projects some of which have yielded very interesting findings,” commented Madhur Garg, MD, Clinical Director of Radiation Oncology, Director of Montefiore-Einstein’s Proton Therapy Program and Co-Director of Stereotactic Radiation Therapy Program at Montefiore Medical Center, Bronx, NY.

Data from the RSSearch Patient Registry has fueled 15 publications to date, including a recent publication by Raj Singh et al in the July 2019 issue of the American Journal of Clinical Oncology titled, “Clinical Outcomes Following Stereotactic Body Radiation Therapy (SBRT) for Stage I Medically-Inoperable Small-Cell Lung Carcinoma: A Multi-Institutional Analysis from the RSSearch Patient Registry.”

“The RSSearch® Patient Registry has enabled Sir Charles Gairdner hospital to collect clinical data for SRS/SBRT patients treated at our facility in Australia and has allowed clinicians and research staff to analyse patient and treatment data and to link this with patient-reported outcomes and treatment results. We have already examined our experience treating patients with localised prostate cancer and have published results. Participating in the Registry has also provided the opportunity to evaluate the effectiveness of our local patient management practices and helped us develop data-driven treatment guidelines. The process has been a huge help in working towards prospective clinical trials,” stated Tammy Corica, PhD, Clinical Trials Manager, Radiation Oncology Clinical Trials & Research Unit, Sir Charles Gairdner Hospital, Nedlands, Australia.

The RSSearch database collects information including patient demographics, lesion characteristics, treatment practices and outcome information including local control, disease progression, survival, toxicity and patient-reported quality of life information. Aggregate data analysis has resulted in several publications on clinical outcomes for radiosurgery treatment of lung tumors, liver metastases, metastatic brain tumors, recurrent head and neck cancer and prostate cancer.

The RSSearch Registry is managed by the RSS and the RSSearch Clinical Advisory Committee, made up of professionals involved in the management and care of patients treated with SRS/SBRT. The registry currently has 26 active sites and more than 80 trained users. Participation in the registry is voluntary and all centers treating patients with SRS/SBRT clinically are encouraged to participate. RSSearch is listed on ClinicalTrials.gov (Identifier (NCT number): NCT01885299).

Interested centers should contact Jan Jenkins, RN, Clinical Program Manager at the Radiosurgery Society at jjenkins@therss.org.

About The Radiosurgery Society®

The Radiosurgery Society (RSS) – a non-profit, independent, multi-disciplinary organization of surgeons, radiation oncologists, physicists, and allied professionals, who are dedicated to advancing the science and clinical practice of radiosurgery. Originally formed in 2002 and becoming 501(c)(6) in 2008, the Radiosurgery Society today (http://www.therss.org) represents approximately 700 members who perform stereotactic body radiotherapy and radiosurgery in hospitals and freestanding centers throughout the world.

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Joanne N. Davis, PhD
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