Singulair Asthma Market to 2023 – Etiology, Pathophysiology, Diagnosis & Treatment Overview in New Report Available at

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Singulair Asthma Market

Singulair Asthma Market

Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan and Australia.

Singulair, developed by Merck, is a CysLT1 receptor inhibitor, blocking the physiologic actions of leukotriene D4 (LTD4). LTD4 belongs to the family of Cys-LTs, which are mediators released from a variety of cells, including mast cells and eosinophils, and which bind to the family of CysLT receptors. Several studies have determined that there are higher concentrations of Cys-LTs in the airways and urine of asthmatics compared with non-asthmatic individuals. The production of CysLTs is increased in asthmatics, particularly during the early phase of bronchoconstriction that follows allergen challenge. Cys-LT signaling results in airway edema, smooth muscle contraction, and aberrant immune cell activity.

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The asthma market saw very slow growth over the past decade, as it has become saturated with relatively efficacious standard therapies, such as short-acting beta-agonists (SABAs), inhaled corticosteroids (ICSs), inhaled corticosteroids and long-acting beta-agonists (ICS/LABAs), and leukotriene modifiers, and has also been facing increasing generic competition. However, the launch of seven novel targeted biologic agents and once-daily ICS and ICS/LABA therapies delivered by the next-generation inhalers will strongly drive the market growth over the next 10 years. The biologic agents will not only reshape the market growth, but will also mark the beginning of a new era of a personalized approach to asthma treatment. The realization that asthma is a very heterogeneous disease is highly reflected in the rich assortment of these targeted therapies in the late-stage pipeline.

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  •     Overview of Asthma, including epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines as well as an overview on the competitive landscape.
  •     Detailed information on Singulair including product description, safety and efficacy profiles as well as a SWOT analysis.
  •     Sales forecast for Singulair for the top eight countries from 2013 to 2023.
  •     Sales information covered for the US, France, Germany, Italy, Spain, the UK, Japan and Australia.

Reasons to Buy

  •     Understand and capitalize by identifying products that are most likely to ensure a robust return
  •     Stay ahead of the competition by understanding the changing competitive landscape for Asthma
  •     Effectively plan your M&A and partnership strategies by identifying drugs with the most promising sales potential
  •     Make more informed business decisions from insightful and in-depth analysis of Singulair performance
  •     Obtain sales forecast for Singulair from 2013-2023 in top eight countries (the US, France, Germany, Italy, Spain, the UK, Japan and Australia)

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Table of Contents
1 Table of Contents
1.1 List of Tables
1.2 List of Figures

2 Introduction
2.1 Catalyst
2.2 Related Reports
2.3 Upcoming Related Reports

3 Disease Overview
3.1 Etiology and Pathophysiology
3.1.1 Etiology
3.1.2 Pathophysiology
3.1.3 Prognosis
3.1.4 Quality of Life
3.2 Symptoms

4 Disease Management
4.1 Diagnosis and Treatment Overview
4.1.1 Diagnosis
4.1.2 Treatment Guidelines, Clinical Practice, and Leading Prescribed Drugs
4.1.3 Clinical Practice

5 Competitive Assessment
5.1 Overview
5.2 Strategic Competitor Assessment

6 Singulair (montelukast)
6.1 Overview
6.2 Efficacy
6.3 Safety
6.4 SWOT Analysis
6.5 Forecast

7 Appendix
7.1 Bibliography
7.2 Abbreviations
7.3 Methodology
7.4 Forecasting Methodology
7.4.1 Diagnosed Asthma Patients
7.4.2 Percent Drug-Treated Patients
7.4.3 General Pricing Assumptions
7.4.4 Individual Drug Assumptions
7.4.5 Generic Erosion
7.5 Physicians and Specialists Included in This Study
7.6 About the Authors
7.6.1 Author
7.6.2 Author/Reviewer
7.6.3 Reviewer
7.6.4 Global Head of Healthcare
7.7 About GlobalData
7.8 Disclaimer

List of Tables
Table 1: Symptoms of Asthma
Table 2: Treatment Guidelines for Asthma by Country
Table 3: Most Prescribed Drugs for Asthma by Class and Disease Severity in the Global Markets, 2013
Table 4: Dosing of Common ICSs for Adult Asthma Therapy to Achieve Equivalent Therapeutic Potency
Table 5: Recommended Low Daily Dose of ICSs in Children with Asthma Under Five Years of Age
Table 6: Leading Treatments for Asthma, 2014
Table 7: Product Profile - Singulair
Table 8: Efficacy - Singulair+Pulmicort Versus Double-Dose of Pulmicort
Table 9: Safety of Singulair+Pulmicort Compared With a Double Dose of Pulmicort
Table 10: Singulair SWOT Analysis, 2014
Table 11: Global Sales Forecast ($) for Singulair, 2013-2023
Table 12: High-Prescribing Physicians (non-KOLs) Surveyed, By Country

List of Figures
Figure 1:Stepwise Disease Management Approach for Asthma in Adults
Figure 2: Stepwise Disease Management Approach for Asthma in Children Age Five and Younger

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Ritesh Tiwari
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