The growing interest in unraveling viral vector quality metrics beyond yield increase via raw titers will be discussed, with an emphasis on the importance of functional viral yield.
TORONTO, Ontario (PRWEB) May 24, 2023
Viral-based gene therapies comprise a key segment of the biotherapeutic landscape and are highly promising advancements for the treatment of complex and rare diseases. While adeno-associated virus (AAV) has emerged as the leading delivery vehicle for gene therapy, its growing demand has significantly strained the manufacturing supply. Viral medicine manufacturers have sought various innovative solutions to resolve this manufacturing bottleneck; however, there is mounting evidence that antiviral defenses are an important but often overlooked barrier to viral vector manufacturing. This intrinsic cellular immunity that is partially, if not wholly, present in manufacturing cell lines has surfaced as a key modulator for viral vector yield and quality.
This webinar will address the cascading impacts of antiviral defenses on viral vector manufacturing. The growing interest in unraveling viral vector quality metrics beyond yield increase via raw titers will be discussed, with an emphasis on the importance of functional viral yield.
Register for the webinar to learn about the impact of antiviral defenses on viral vector production systems, a solution to tackle viral defenses with a simple media additive and the future of viral vector manufacturing for the biotech industry.
Join experts from Virica Biotech, Dr. Jean-Simon Diallo, CEO; Dr. Jondavid de Jong, VP Scientific Operations; and Benjamin McLeod (Moderator), Technical Lead, for the live webinar on Tuesday, June 13, 2023, at 11am EDT (4pm BST/UK).
For more information, or to register for this event, visit Viral Vector Manufacturing — Are Antiviral Defenses the Missing Link to Scalability?
ABOUT VIRICA BIOTECH
Virica is the first company to develop and commercialize Viral Sensitizers (VSE™) as a solution to the challenge of Antiviral Defenses in the manufacturing of viral vectors. VSEs are patented small molecules, including known drugs and novel synthetic compounds, that transiently attenuate antiviral pathways in cells and, thus, can increase both virus production and the therapeutic efficacy of viral medicines.
Virica’s VSE platform evolved from research conducted by Dr. Jean-Simon Diallo, Virica’s Scientific Founder and CEO and a world-recognized leader in oncolytic viral therapies, at the Ottawa Hospital Research Institute (OHRI). Dr. Diallo and his team have developed unique high-throughput virology methods that have to date identified over 100+ VSEs.
Our services include formulation development with off-the-shelf or custom solutions as well as in-house evaluation or at-site evaluation support.
Learn more at viricabiotech.com or visit us on LinkedIn.
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