Nerium International Partners with Signum Biosciences for Exclusive Use of SIG-1191™

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Breakthrough molecule is key ingredient in Nerium’s new Age-Defying Eye Serum

Nerium International, a relationship marketing company specializing in scientifically advanced, age-defying products, has announced its latest weapon in the fight against aging: SIG-1191.

The patent-pending molecule, developed by Princeton University biochemist Dr. Jeffry Stock and the team at Signum Biosciences, is the key ingredient in Nerium’s new Age-Defying Eye Serum. It was developed specifically to target the signs of aging around the eyes, as well as its underlying causes.

SIG-1191 acts as a powerful antioxidant and skin hydrator. In Age-Defying Eye Serum, SIG-1191 combines with other ingredients, such as I-FIL4R™ derived from white lily and Brazilian ginseng, and aloe barbadensis leaf juice, to deliver both immediate and long-term anti-aging results.

Age-Defying Eye Serum with SIG-1191 provides the following benefits:

  • delivers immediate reduction in the appearance of fine lines and wrinkles
  • supports the skin’s natural structure
  • fights the appearance of dark circles, puffiness and lines and wrinkles
  • matches the skin’s natural pH level, ensuring optimal skin health
  • firms and brightens the appearance of the eye area
  • is ideal for all skin types (dermatologist and ophthalmologist tested)

In independent clinical trials, participants using Age-Defying Eye Serum showed an immediate reduction in the appearance of crow’s feet, puffiness and dark circles – and showed continued improvement with four weeks of use.

“We’re very proud of our clinical studies,” said Chief Marketing Officer Amber Olson Rourke. “These are third-party, scientific studies that prove the effectiveness of this product.”

SIG-1191 is just the latest in a series of important anti-aging discoveries by Signum Biosciences, developed exclusively for Nerium products. Signum discovered SIG-1273™, a dual-action molecule that boosts the skin’s ability to combat the oxidative stress that can lead to fine lines and wrinkles. It can be found in Nerium’s Optimera Formula™ of Age-Defying Night Cream, Age-Defying Day Cream and Firming Body Contour Cream in Canada and Mexico, as well as Nerium’s Optimera® Plus Formula of Age-Defying Night Cream and Age-Defying Day Cream in Korea. Signum also developed the patented EHT extract, the key ingredient in EHT Age-Defying Supplement, Mind Enhancement™ Formula, which helps strengthen neural connections and help keep the brain in its optimal state. Nerium International’s agreement with Signum Biosciences ensures customers have access to exclusive age-defying products that deliver real results.

“We have the global exclusive rights for every single one of our patents,” said Nerium International Founder and CEO Jeff Olson. “Because we license the patents and the sourcing, no one else can replicate our products.”

For more information about Age-Defying Eye Serum and its key ingredient, SIG-1191, visit For more information about Nerium International partner Signum Biosciences, go to

About Nerium International
Nerium International, LLC, headquartered in Addison, Texas, is a relationship marketing company that markets breakthrough products validated by science. Since its August 2011 launch, Nerium has reached record-breaking sales and earned industry accolades, while building a loyal customer base of millions in the U.S., Canada, Mexico and South Korea. Nerium debuted on Inc. magazine's 34th annual Inc. 500 List of America's fastest-growing, privately held companies as the No.1 consumer products and services company. Nerium was also ranked No.12 on the list overall. Led by an award-winning executive team with more than 220 years of collective industry experience, Nerium International is committed to developing and distributing anti-aging products that are rooted in real science, produce real results and improve consumers' lives. For more information, please visit

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Brooke Ezell
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