SCIEX Addresses the Challenges of Vitamin D Measurement Standardization

Share Article

Through this educational webinar, which LabRoots will host October 18, attendees will learn to evaluate the performance of immunoassay and LC-MS/MS methods for 25-OH vitamin D.

Gary Horowitz, MD Medical Director, Informatics and POCT Associate Medical Director, Clinical Chemistry Department of Pathology and Laboratory Medicine Tufts Medical Center

The team has arranged for Dr. Gary Horowitz to present work done in collaboration with SCIEX. Dr. Horowitz received his bachelor's degree in chemistry from Harvard College and his medical degree from Harvard Medical School. After completing a clinical pathology residency at Beth Israel Hospital in Boston, he went on to become the Director of Clinical Chemistry. In 1996, following the merger with New England Deaconess Hospital, he became the Director of Clinical Chemistry for the newly formed Beth Israel Deaconess Medical Center. In 2017, he joined the Department of Pathology and Laboratory Medicine at Tufts Medical Center as the Director of Informatics and Point of Care Testing, Associate Director of Clinical Chemistry, and Visiting Associate Professor of Pathology and Laboratory Medicine at Tufts University School of Medicine.

Over the past decade, 25-OH vitamin D has become one of the most common assays requested by physicians. The increase in testing volume is driven by risk-association studies linking vitamin D not only to calcium homeostasis, but also to cardiovascular disease, stroke, cancer, autoimmune disease, and even fractures. Measurement is complicated by the existence of two forms of vitamin D, as well as by the presence of epimers of both forms.

Standardization has only recently been introduced, and proficiency testing, though available, reflects the poor state of the art. In this session, we will delve into the details of vitamin D measurement, aided by results from a recent study using the first FDA-cleared via the de novo pathway 25-OH vitamin D assay for mass spectrometry. This webinar will discuss ways of acknowledging, and dealing with, limitations of the various assays.

Participants of this webinar will gain a better understanding of the need for accuracy in testing total 25-OH-vitamin D. they will also learn to recognize the importance of standardization efforts in vitamin D and how to identify the challenges of external quality control surveys face in testing accuracy.

LabRoots will host the webinar October 18, 2017, beginning at 8:00 a.m. PDT, 11:00 a.m. EDT. To learn more about this event, discover the continuing education credits offered, or to register for free, click here.

SCIEX helps to improve the world we live in by enabling scientists and laboratory analysts to find answers to the complex analytical challenges they face. The company's global leadership and world-class service and support in the capillary electrophoresis and liquid chromatography-mass spectrometry industry have made it a trusted partner to thousands of the scientists and lab analysts worldwide who are focused on basic research, drug discovery and development, food and environmental testing, forensics and clinical research.

With over 40 years of proven innovation, SCIEX excels by listening to and understanding the ever-evolving needs of its customers to develop reliable, sensitive and intuitive solutions that continue to redefine what is achievable in routine and complex analysis. For more information, please visit

SCIEX social: Twitter: @SCIEXnews, LinkedIn and Facebook.

About LabRoots:
LabRoots is the leading scientific social networking website and producer of educational virtual events and webinars. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.

Share article on social media or email:

View article via:

Pdf Print

Contact Author

Karen Sorenson
LabRoots, Inc.
+1 (619) 861-0590
Email >
Visit website