Pathways Bioscience Announces Product Release of Their Next-Generation Nrf2-Activating Dietary Supplement PB125™

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Pathways Bioscience releases PB125™ into the US market. PB125™ is a new dietary supplement formulated to rebalance cell protection mechanisms and was developed by utilizing Pathways Bioscience’s Nrf2.0™ technology.

Pathways Bioscience LLC, a bioscience company focused on discovering and developing dietary supplements and pharmaceutical products that act on gene transcription pathways, announced today that it has launched its PB125™ dietary supplement product for sale in the US market. PB125™ activates the Nuclear Factor, Erythroid 2-Like-2 (NFE2L2, also known as Nrf2) transcription factor pathway, which regulates the expression of a large group of cell protective and anti-inflammatory genes.

“We are thrilled to make our next generation Nrf2 activating dietary supplement PB125™ available to US consumers,” said President and CEO of Pathways Bioscience, Brooks M Hybertson, PhD. “We have worked hard in our laboratory over the past few years to develop our Nrf2.0™ Technology and we have utilized that new knowledge to create our PB125™ dietary supplement.”

Pathways Bioscience was launched in 2014 to pursue R&D on ways to support healthy aging by influencing transcription factors and gene expression and to develop new products based on their work. They have already hit several important milestones based on their work on the Nrf2 pathway. In 2017 another one of their Nrf2-activating formulations that they developed using Nrf2.0™ Technology, PB123™, was licensed and launched into the market in Mexico by their partner Activz Global, LLC. Also in 2017, Pathways Bioscience was the recipient of two SBIR (Small Business Innovation Research) grants from the US National Institutes of Health to develop approaches to improving health outcomes by influencing Nrf2 activation and Nrf2-dependent gene expression.

The scientific leader of Pathways Bioscience, Dr. Joe M McCord had this to say, “We have learned a great deal about the Nrf2 transcription factor pathway in the past few years, much more than we knew ten years ago. This new information about the steps in the activation of Nrf2 and enhanced expression of cell-protective genes led us to decide to develop PB125™ as a new, next-generation, Nrf2-activating dietary supplement to support healthy aging.”

About Pathways Bioscience
Pathways Bioscience LLC is a bioscience company focused on discovering and developing new agents, both small molecule drugs and dietary supplements, that influence gene expression pathways and exert beneficial effects, with particular emphasis on the Nrf2 transcription factor, known as the master regulator of cell protection mechanisms. These activities are based on the concept that the best way to improve healthspan and overcome the health and wellness problems associated with aging is to support the body’s own defense mechanisms that allow it to protect and rebalance itself. The company's headquarters are in Aurora, Colorado. For further information regarding Pathways Bioscience, LLC, please visit the Company’s Website at

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Brooks Hybertson
Pathways Bioscience, LLC
+1 (720) 372-4815
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