A University of Nebraska-Lincoln Clinical Trial on Natreon’s Patented PrimaVie® (Shilajit) Showed Increased Retention of Muscular Strength and Decreased Hydroxyproline

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Natreon's Patented PrimaVie® (Shilajit) Promoted the Retention of Muscular Strength and a Decrease in Hydroxyproline (a marker of collagen degradation) in a Recently Published Clinical Trial at The University of Nebraska-Lincoln.

“The results of our study demonstrated the robust, positive effects of PrimaVie shilajit on important aspects of Sports Nutrition including strength, fatigue, and the maintenance of collagen health.”

Natreon, a leader in Ayurvedic ingredient research and innovation, is proud to announce the latest publication on patented PrimaVie shilajit showing benefits of PrimaVie supplementation on maintaining muscular strength and hydroxyproline levels in recreationally active men. This study marks the ninth clinical trial on PrimaVie and is published in the January 2019 edition of The Journal of the International Society of Sports Nutrition by renowned researchers in Sports Nutrition from the University of Nebraska-Lincoln, Dr. Joshua Keller and Dr. Terry Housh. PrimaVie shilajit expands on a rich history of use of shilajit in Ayurveda by investing in modern science, clinical efficacy and nutrient standardization to achieve a profile consisting of urolithins, fulvic acid and micro-minerals. In addition, GRAS affirmed PrimaVie is the only organic and Non-GMO project verified shilajit extract on the market.

This U.S. based study, conducted at The University of Nebraska-Lincoln, was an 8-week, randomized, double-blind, placebo-controlled, clinical trial to examine the impact of PrimaVie on fatigue-induced percent decline in strength, and concentric peak torque and hydroxyproline levels. Subjects were all recreationally active, healthy males randomized to receive PrimaVie at 500 mg/day, 250 mg/day or a placebo. In summary, the results of the study demonstrated that 8 weeks of PrimaVie shilajit supplementation at 500mg promoted the retention of muscular strength following the fatiguing protocol and decreased baseline hydroxyproline, which is a marker for collagen degradation. This suggested that the group supplementing with 500mg of PrimaVie shilajit was more resistant to fatigue and retained a greater level of maximal muscular strength.

“The results of our study demonstrated the robust, positive effects of PrimaVie shilajit on important aspects of Sports Nutrition including strength, fatigue, and the maintenance of collagen health.” Dr. Terry J. Housh, Professor and Director of the Human Performance Laboratory, Department of Nutrition and Health Sciences, University of Nebraska-Lincoln.

Prior to the UNL trial, Natreon had conducted 8 clinical studies on PrimaVie to unlock the full potential of this important ayurvedic nutrient.

“We are very excited about these results of from the University of Nebraska-Lincoln (UNL) as this enhances our growing body of research highlighting PrimaVie’s role in collagen support. Our previous clinical studies at Ohio State University, discovered that PrimaVie upregulates collagen and other extra cellular matrix protein genes synergistically with exercise. Furthermore, the UNL study results show PrimaVie supplementation decreases degradation of collagen in the body as evidenced by decreases in hydroxyproline. These are significant findings because it shows that PrimaVie can work two ways to enhance collagen in the body and additionally it upregulates other extra cellular matrix protein genes.” said Dr. Sanni Raju, CEO of Natreon.

The new study reaffirms PrimaVie’s use in sports performance products and expands its benefits into healthy aging and strength by demonstrating reduction in hydroxyproline (a marker of collagen degradation) along with increases in strength in athletic males.

“Sports Nutrition is a primary focus for Natreon and PrimaVie is our lead ingredient in the category given its historical use as an adaptogen for energy. PrimaVie’s historical use in Ayurveda, positive clinical trial results, natural, botanical, organic and non-GMO project verified attributes, clearly differentiates PrimaVie from other ingredients in the market,” said Bruce Brown, President of Natreon.

Click to view full published study

For more information on PrimaVie or Natreon’s full portfolio of ingredients, please email info@natreoninc.com.

About PrimaVie®
PrimaVie Biome Optimized Shilajit™ is sourced and purified from distinct biological ecosystems (biomes) and processed using sustainable green chemistry (water extraction), to provide optimal efficacy and bioactive diversity. This proprietary mineral extract has been studied in 9 randomized, double-blind, placebo-controlled human clinical trials. PrimaVie is a powerful adaptogen standardized to achieve its proprietary composition consisting of urolithins (DBPs), fulvic acid and over 40 micro-minerals. PrimaVie supports many health benefits such as boosting testosterone, strength, energy, and endurance levels, while also up-regulating the genes responsible for collagen synthesis. It has excellent applications in supplements, sports nutrition and healthy aging products. PrimaVie is the only organic, Non-GMO project verified, and GRAS affirmed shilajit extract on the market. Visit: https://natreoninc.com/primavie-shilajit/.

About Natreon:
Natreon is a leader in nutritional ingredient innovation, quality and research. Trusted by manufacturers for over 20 years, Natreon’s patented ingredients are derived from nature and founded on evidence-based Ayurveda. Committed to quality, its extracts are purified and standardized using proprietary process technology and controls that result in optimal levels of bioactive constituents. Natreon’s ingredients have been tested in multiple clinical and safety studies to ensure safety, efficacy and authenticity. Natreon brings storied knowledge and expertise in botanical cultivation and extraction, and its ingredients are sustainably sourced through an integrated supply chain to ensure quality and potency. Natreon has its global headquarters in New Jersey and a state-of-the-art R&D facility in Kolkata, India. For more information, visit: https://natreoninc.com/.

Dr. Sanni Raju, CEO/Chairman or Bruce Brown, President
2-D Janine Place
New Brunswick, NJ 08901
732-296-1080- -

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