Bringing the Clinical Trial to the Patient in Preclinical Alzheimer’s Disease, Upcoming Webinar Hosted by Xtalks

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In this free webinar, learn about important factors for designing an Alzheimer’s disease trial that includes remote cognitive assessment. Attendees will learn about characteristics of cognitive tests that make them optimal for use in remote assessment contexts. The featured speakers will discuss quality issues that can influence cognitive data collected from remote assessment contexts. Attendees will gain insights into the appropriateness of Cogstate tests for use in culturally diverse populations. The speakers will discuss opportunities for new trial design arising from application of remote cognitive assessments.

Clinical trial teams now need testing solutions that are effective and equivalent when deployed outside of the clinical site.

With the first demonstration that anti-amyloid therapies can slow amyloid accumulation and reduce clinical disease progression in symptomatic Alzheimer’s disease, there is increasing focus on the extent to which disease modifying therapies, applied very early in AD, may delay symptom onset itself.

With focus turning to clinical trials in the preclinical stage of Alzheimer’s disease, clinical trial design is faced with new challenges and new opportunities. The requirement for identifying abnormal Alzheimer’s disease biology in cognitively unimpaired adults is being made easier with the industrialization of blood-based biomarkers for amyloid and tau. In the same vein, engaging, screening, recruiting and even assessing clinical status in cognitively unimpaired adults is facilitated through use of remote clinical assessment.

Clinical trial teams now need testing solutions that are effective and equivalent when deployed outside of the clinical site. Utilizing remote testing allows participants to be assessed from the comfort of their home, typically reducing the number of site visits, and supporting faster and more diverse recruitment which allows studies to be extended to include samples from underrepresented populations.

Cogstate technologies have been used in remote contexts in clinical trials and research for decades. This experience provides the basis for their current application in Phase III registration of trials of disease-modifying therapies in preclinical Alzheimer’s disease.

This webinar will consider the types of remote cognitive assessments that can be applied in clinical trials, aspects of trial design to which they apply and the methodological issues that require consideration when cognitive assessments are conducted remotely. The featured speakers conclude with consideration for the potential opportunities afforded by use of remote cognitive assessment in preclinical Alzheimer’s disease.

Join experts from Cogstate, Paul Maruff, PhD, Chief Innovation Officer; and Chris Edgar, PhD, Chief Science Officer, for the live webinar on Thursday, December 15, 2022, at 1pm EST (10am PST).

For more information, or to register for this event, visit Bringing the Clinical Trial to the Patient in Preclinical Alzheimer’s Disease.


Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year, thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

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Vera Kovacevic
Tel: +1 (416) 977-6555 x371

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