Cardiac Safety in Oncology Drug Development – The Role of ECG and Cardiac Imaging Endpoints From a Cardio-Oncology Perspective, Upcoming Webinar Hosted by Xtalks

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In this free webinar, the featured speaker will introduce cardio-oncology in oncology drug development and discuss regulatory consideration and trial design approaches related to ECG endpoints such as ECG-PKconcentration. Attendees will learn about cardiac imaging endpoints and considerations around the specific cardiac imaging modality to implement in a clinical trial.

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Cardio-oncology is most frequently associated with a clinical focus on cardiovascular issues associated with the treatment and management of cancer patients, as many oncology therapeutic agents are also cardiotoxic. The collaboration and integrated treatment approach between the fields of cardiology and oncology has led to a proactive treatment approach which, along with improved cancer treatments, has also improved survival rates and quality life for cancer patients. This clinical collaboration is paralleled in the approach to the development of new oncologic therapeutic agents.

Cardiac safety endpoints are important considerations in the development plan for an oncology treatment. With a focus on establishing a benefit-risk profile of new compound and/or the use of an existing treatment for a different indication, there is a need to develop a strategy to define the developing treatment’s cardiac safety profile. Cardiac safety endpoints/modalities in oncology drug development include electrocardiography (ECG), hemodynamics, cardiac imaging (i.e. echo, muga) and laboratory cardiac biomarkers. This webinar will focus on the integration and approaches to implementing ECG and cardiac imaging endpoints into an oncology study and development plan.

Join Jeff Heilbraun, VP, Medical and Scientific Affairs Cardiac Safety Service, Bioclinica and M. Barbara Srichai-Parsia, Associate Professor of Medicine & Radiology , Georgetown University School of Medicine, in a live webinar on Wednesday, September 30, 2020 at 11am EDT (4pm BST/UK).

For more information or to register for this event, visit Cardiac Safety in Oncology Drug Development – The Role of ECG and Cardiac Imaging Endpoints From a Cardio-Oncology Perspective.


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Sydney Perelmutter
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