Cereset Research Exposes the Secrets of Traumatic Stress Hidden in the Brain

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Effects of an Allostatic Closed-Loop Neurotechnology (HIRREM) on Brain Functional Connectivity Laterality in Military-Related Traumatic Stress

Cereset Research shares functional MRI brain maps of brain functional connectivity laterality in military-related traumatic and post-traumatic stress

Cereset Research shares brain maps of brain functional connectivity laterality in military-related traumatic stress

HIRREM® (the legacy research technology of Cereset® - a Brain State Company) was utilized by the Wake Forest School of Medicine to study symptoms of traumatic stress in military personnel before and after use of Cereset (legacy) intervention. (https://onlinelibrary.wiley.com/doi/10.1111/jon.12825)

Whole brain, resting state magnetic resonance imaging (MRI) was done pre- and post- Cereset intervention. Significant effects on brain network connectivity have been previously reported (https://onlinelibrary.wiley.com/doi/full/10.1111/jon.12571). For the current study, lateralization of brain connectivity was analyzed. Lateralization here refers to the distribution of brain connections within the right, and left side, or to the opposite side. This is important because common lobes in the right and left hemispheres of the brain execute different functions. Of note for these results, the parasympathetic division of the autonomic nervous system (which we think of as the “brake to rest and digest”) is managed primarily on the left, and the sympathetic division (which we think of as the “gas to go”) is driven primarily on the right.” Thus, the dominant left is a “freeze or numbing” response indicator, and in contrast, a dominant right is the “fight or flight” response indicator.

Asymmetries were identified at baseline, along with changes in lateralization patterns after Cereset. Significant correlations were seen between whole-brain lateralization and symptoms of posttraumatic stress. These findings help to understand the effects of and how best to treat traumatic stress.

The brain is the organ of central command which activates and manages autonomic responses to trauma and stress. Results of this study support the model of bihemispheric autonomic management of traumatic stress (BHAM), proposed by Brain State and Wake Forest 6 years ago (https://www.frontiersin.org/articles/10.3389/fpsyg.2014.00843/full). Regulated connections of the brain appear to be the upstream driver of health and wellbeing. When connections between hemispheres are more balanced, individuals are healthier.

Of note is the basis for this brain movement towards a healthier pattern. Cereset merely reflects the brain’s own electrical patterns using engineered tones to represent dominant brain frequencies. The client receiving Cereset is comfortably seated in a reclining chair to listen to the brain generated tones or BrainEcho®. This supports the brain to relax, to change, and to reset itself to improve balance and symmetry, which is associated with reduced symptoms of traumatic stress.

Many prior clinical studies have demonstrated benefits associated with the use of Cereset for symptoms of insomnia, depression, stress, anxiety, concussion, hot flashes, postural orthostatic tachycardia, and migraine. The current and previous clinical trials also included objective outcome measures such as heart rate variability to demonstrate significant improvement in autonomic function. Symptom benefits were durable for up to 6 months in the current study, and autonomic improvement was durable through the final follow-up visit at 4 months in a placebo-controlled trial for insomnia.

The addition of the MRI lateralization findings reported in this study and the correlation with symptoms not only support the BHAM model but also point to a mechanism of effect for the clinical benefits previously reported with Cereset. Symptoms associated with trauma, stress, and allostatic load now affect a majority of the population. Cereset noninvasively supports the brain to balance and regulate itself with resulting benefits for psychological symptoms of traumatic stress and improved autonomic function.

Funding for this study was provided by:
The Susanne Marcus Collins Foundation Inc., Joint Capability Technology Demonstration Program within the Office of the Under Secretary of Defense, US Special Operations Command, and the Wake Forest Clinical and Translational Science Institute.

For more information about Cereset Research / HIRREM clinical research studies, and other innovations in closed-loop neurotechnology / balanced neuromodulation, visit:

Cereset is a wellness company that helps clients relax their brains to manage stress, restore hope and achieve restful sleep through its patented BrainEcho® technology. Cereset empowers the brain to reset itself as it hears and “sees” its own reflection. The global technology leader in non-invasive brain self-restoration and optimization, Cereset enables the brain to fully relax and naturally rebalance itself from the inside out. There is no outside intervention, stimulus or medication of any kind – the brain does its own work while the client naps or relaxes quietly in a comfortable chair. To schedule an appointment at a Cereset client center, or to learn more, visit https://cereset.com

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Lee Gerdes, CEO
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