Crystal Structure Determination in Solid Form Drug Development, Upcoming Webinar Hosted by Xtalks

Share Article

In this free webinar, the featured speaker will discuss crystal structure solutions used from first synthesis, to drafting of patents of solid forms. The presentation will highlight the key moments in development when various methods of structure solution are used.

Xtalks Life Science Webinars

Growing a sufficiently large, good quality, single crystal can sometimes still be a challenge and a bottleneck, even when crystals smaller than 100-μm can now routinely be used.

Join this live webinar on Tuesday, September 22, 2020 at 1pm EDT (10am PDT), presented by Dr. Steef Boerrigter, Senior Research Scientist, AMRI.

Single crystal structure solution using X-ray diffraction analysis (SC-XRD) plays an important role in drug development. SC-XRD fully elucidates the molecular structure and can be used to confirm successful chemical synthesis of the molecule. Many drug molecules are chiral. In addition to being the most reliable, SC-XRD is the only generally applicable method to determine the absolute configuration, i.e. the three-dimensional structure of the molecular bonds.

Growing a sufficiently large, good quality, single crystal can sometimes still be a challenge and a bottleneck, even when crystals smaller than 100-μm can now routinely be used. Several growing techniques will be discussed in this upcoming webinar.

Given high resolution powder X-ray diffraction (PXRD) data, most often the unit cell parameters and space group can be determined by finding an indexing solution to the observed peak positions, also known as indexing. The resulting unit cell volume can be used to identify the contents and stoichiometry, and the index of a PXRD pattern reveals if extraneous Bragg peaks exist, indicating form impurities.

In patents, solid forms are usually claimed by lists of characteristic peaks in the PXRD. Collecting PXRD data is often straightforward, though pitfalls exist.

Join this webinar to learn more!

For more information or to register for this event, visit Crystal Structure Determination in Solid Form Drug Development.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com
For information about hosting a webinar visit http://xtalks.com/why-host-a-webinar/

Share article on social media or email:

View article via:

Pdf Print

Contact Author

Ayesha Rashid
Xtalks
+1 (416) 977-6555 x 272
Email >
Visit website