CTScreen: A 3D-Engineered Cardiac Tissue System for Automated Perfusion, Stimulation and Contractility Measurement, Upcoming Webinar Hosted by Xtalks
In this webinar, the featured speakers will discuss how cardiac twitch force can be measured using Novoheart's elastomer bioreactors in the CTScreen system, and which parameters can be extracted to assess cardiac contractility, relaxation, and arrhythmogenicity. They will offer insight into building an automated experimental testing protocol that utilizes the features of the system. The presentation will also include what the experimental data collected using the CTScreen system looks like, and how it is processed with the software. Data collected on the system can be leveraged for preclinical tox and efficacy screening in the context of human rather than animal tissues for improved accuracy, IND and clinical designs.
TORONTO, July 8, 2021 /PRNewswire-PRWeb/ -- The CTScreen is Novoheart's newest commercial platform that measures true contractility of 3D-engineered cardiac tissue under physiological conditions. The system allows quantitative assessment of the contractile response of healthy and diseased tissues, as required to study drug toxicity and efficacy. It also allows for tissue fabrication and functional characterization with minimal handling by the user, yielding high-content measurements of twitch force without complicated instrumentation.
Biomimetic 3D cardiac tissues with integrated force-sensitive end-posts can be constructed from stem cell-derived or primary cardiomyocytes using the custom elastomer cassettes provided. The tissue cassette can then be installed and analyzed on the CTScreen setup. The CTScreen comes with fully-integrated acquisition and analysis software, with real-time data readout for quick monitoring of functional responses.
In this Xtalks webinar presentation, experts from Novoheart will discuss the development of the CTScreen system's unique features such as the glass perfusion chamber, multi-tissue bioreactors for running several tissues in parallel, automated protocol table and user-friendly software. They will also present sample data collected using the system, and ongoing efforts to increase throughput and expand capabilities for users interested in myocardial physiology, disease modelling, cardiotoxicity and drug discovery and development.
Join Novoheart leaders, Dr. Kevin Costa, CSO and Co-Founder; and Dr. Erin Roberts, Team Head of Biomedical Engineering, for the live webinar on Tuesday, July 27, 2021 at 12pm EDT (5pm BST/UK).
For more information, and to register for this event, visit CTScreen: A 3D-Engineered Cardiac Tissue System for Automated Perfusion, Stimulation and Contractility Measurement.
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