Deep Phenotyping of the Human Liver for NAFLD (NASH) Target Discovery, Upcoming Webinar Hosted by Xtalks

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In this free webinar, the featured speakers will discuss the translational trends in deep phenotyping genomics and the applications of spatial sequencing and imaging AI to dissect pathological changes in the liver with age and obesity. They will discuss how difficult samples (including FFPE-derived RNA) can be analyzed and how spike-in controls can contribute to RNA-Seq quality control.

Ochre Bio’s approach is firmly rooted in computational and systems-driven learning. However, the company’s goal is also to decode substantially better, by deep phenotyping of human organs to complement the growing importance of population genetics as a tool to de-risk targets.

Deep phenotyping combines genetics, advanced tissue imaging, cellular genomics (single-cell and spatial sequencing) and machine learning to study disease and gene systems at the tissue level.

Ochre Bio’s approach is firmly rooted in computational and systems-driven learning. However, the company’s goal is also to decode substantially better, by deep phenotyping of human organs to complement the growing importance of population genetics as a tool to de-risk targets. This involves deep phenotyping of human biobanks, high throughput human micro-organ (in vitro) models and entire human organs maintained in organ transplant perfusion devices.

Lexogen provides RNA-Seq services at the expert level, covering the whole workflow from consultation to RNA extraction, library preparation, next-generation sequencing and data analysis. They routinely handle a wide range of RNA input, from standard quality to FFPE-extracted and degraded RNA, stemming from sources like tissues, cell culture, biofluids and single cells. This is matched by standardized and advanced data analyses, as well as the option for automation to handle large-scale projects.

Register for this live webinar on Thursday, April 15, 2021 at 11am EDT (4am BST/UK) to hear Dr. Quin Wills, Co-founder and CSO, Ochre Bio, provide a brief overview of functional genomic trends in drug discovery, followed by a recently completed project to spatially sequence 1,000 human livers over the early NAFLD spectrum. He’ll end with how he believes this can transform the study of age-related chronic diseases that have long silent clinical trajectories before presenting with complications.

For more information, or to register for this event, visit Deep Phenotyping of the Human Liver for NAFLD (NASH) Target Discovery.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year, thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com
For information about hosting a webinar visit http://xtalks.com/why-host-a-webinar/

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Ayesha Rashid
Xtalks
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