Flow Cytometry Tools to Support Cellular Therapies, Upcoming Webinar Hosted by Xtalks

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In this free webinar, the featured speakers will discuss the utility of flow cytometry in applications to support cellular therapy drug development programs. Specifically, it can be used to measure the presence and quantitate cell therapies, simultaneously measuring their activation state and functional readouts. Moreover, while characterizing the cellular therapy, flow cytometry can also be used to measure the patient’s immune response to the drug.

Multi-parameter flow cytometry is a powerful tool for both characterizing the cellular therapy and the patient’s immune response against the cell therapy.

Novel biotherapeutics such as cell therapy pose unique challenges for bioanalysis. Pharmacokinetics, immunogenicity and biomarker testing take on different forms and timing for implementation as compared to “standard” large molecule biotherapeutics. There are a number of different platforms and strategies utilized which will be discussed in this presentation, with a focus on flow cytometry.

Multi-parameter flow cytometry is a powerful tool for both characterizing the cellular therapy and the patient’s immune response against the cell therapy. Exposure, durability and exhaustion of cellular therapies are all components of what most closely aligns with pharmacokinetic analysis of large molecule therapeutics. The ability to detect relatively small numbers of circulating cell therapies and phenotypic characterization of their activation state are all essential for monitoring the cell therapy post-delivery to the patient. The cell therapy can also be monitored for intracellular cytokine production along with other markers of cell activation to determine specific immune functions associated with efficacy.

For the patient’s immune response to the cell therapy, a similar phenotypic and function assessment can be performed from the same sample as long as reagents specific to the cell therapy are available.

Register for this live webinar on Monday, April 12, 2021 at 10am EDT (3pm BST/UK) to hear from experts from BioAgilytix, Jim McNally, Chief Scientific Officer, and Nathan Rudemiller, Manager of Operations, about the capabilities of flow cytometry and case studies of its use in the bioanalysis of cell therapies.

For more information, or to register for this event, visit Flow Cytometry Tools to Support Cellular Therapies.

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Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year, thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com
For information about hosting a webinar visit http://xtalks.com/why-host-a-webinar/

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Ayesha Rashid
Xtalks
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