This webinar will introduce the developmental phases of the GARD assays and discuss the technological origins of the observed high predictive performance, as well as how the assays help industries overcome their specific challenges in safety testing in a broad applicability domain
TORONTO (PRWEB) May 11, 2020
Predictive toxicology is a discipline that aims to proactively identify adverse human health and environmental effects in response to chemical exposure. GARD – Genomic Allergen Rapid Detection – is a next-generation, animal-free testing strategy framework for assessment and characterization of chemical sensitizers. The GARD platform integrates state-of-the-art technological components, including utilization of cell cultures of human immunological cells, omics-based evaluation of transcriptional patterns of endpoint-specific genomic biomarker signatures and machine learning-assisted classification-models.
To this end, the GARD platform provides accurate, cost effective and efficient assessment of skin and respiratory sensitizing capabilities of neat chemicals, complex formulations, mixtures and solid materials. GARD assays are successfully applied throughout the value chain of chemical and life science industries, including safety-based screening of candidates during preclinical research and development, monitoring of protocol changes and batch variations, monitoring of occupational health and for registration and regulatory approval.
This webinar will introduce the developmental phases of the GARD assays and discuss the technological origins of the observed high predictive performance, how the assays help industries overcome their specific challenges in safety testing in a broad applicability domain, and illustrate how GARD assays facilitate efficient decision-making in compliance with the principles of the 3Rs.
For more information or to register for this event, visit Genomics and Machine Learning for In Vitro Sensitization Testing of Challenging Chemicals.
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