Hygieia creates first technology to automate dose adjustment for all common insulin regimens

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d-Nav insulin management program gives people with long-term Type 2 diabetes a clear path to safe, effective insulin use.

We developed a way to make insulin therapy safe and effective through a technology that doesn’t add burden to an already resource-challenged health system. - Eran Bashan, Ph.D., Hygieia CEO

Hygieia is upending the old standard of insulin management for people with Type 2 diabetes. Using artificial intelligence and patented technology, Hygieia’s d-Nav® insulin management program automatically determines how much insulin a patient needs at the time of injection. Patients get the recommended dose when they need it, which helps them better manage their glucose levels.

It’s a dramatic change from today’s standard of care in which a patient’s insulin dose is modified only when he or she can see a physician for evaluation every few months. That creates a barrier to care, because people’s insulin needs are dynamic and often require much more frequent titration.

“Nearly 70 percent of people using insulin to manage their blood sugar levels fail to achieve recommended A1c levels,” said Eran Bashan, Ph.D. and CEO of Hygieia. “So, we developed a way to make insulin therapy safe and effective through a technology that doesn’t add burden to an already resource-challenged health system.”

The d-Nav program uses a handheld device and patented technology to measure glucose, identify glucose patterns and automatically calculate the next individualized insulin dose. Users simply insert their test strip into a handheld device and d-Nav analyzes the information and provides a recommended insulin dose. For many users, the dose changes every few days.

Through titration, d-Nav offers a safe and effective therapy for managing blood glucose levels. Studies have shown that within three months of starting d-Nav, 90 percent of users lowered their HbA1c levels.

Additionally, when insulin is working more effectively, there is an opportunity to move people to less expensive insulin and to reconsider the need for additional, more costly medications. In fact, a health economic study showed1 that people using d-Nav translated into cost savings of approximately $500 per patient, per month.

“When physicians first started prescribing insulin some 100 years ago, it was a medical breakthrough and a life-saving medication for insulin-requiring patients,” said Bashan. “Decades later, the growing number of patients makes it hard to sustain that standard. Hygieia’s d-Nav program serves as a collaborative insulin specialist helping patients safely and effectively manage their blood sugar levels.”

It’s a revolutionary concept designed to enable physicians, both primary care and endocrinologists, the ability to extend their continuous, personalized care to insulin treated patients with Type 2 diabetes without overtaxing office time and resources.

Patients on the d-Nav program receive test strips, lancets, a glucose monitor pre-loaded with the d-Nav app, and unlimited remote monitoring and clinical support. Physicians who prescribe d-Nav receive data and reports on their patients’ status, helping them with ongoing blood sugar management. For more information, contact Hygieia.com.

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1 “Impact of a Novel Insulin Management Service on Non-insulin Pharmaceutical Expenses,” Journal of Health Economics and Outcomes Research, JHEOR 2018;6(1):53-62

About Hygieia/ d-Nav Insulin Management Program
Hygieia’s d-Nav® insulin management program includes an AI-powered application and helps people with Type 2 diabetes use insulin in a safe and effective way. It works by guiding users to adjust their insulin doses – based on blood glucose patterns -- every few days rather than three of four times annually. Studies show that some 90 percent of people using d-Nav® achieve lower A1c within three months. Patients report feeling better; having fewer complications; spending less time at their physician’s office; and potentially lowering their disease management costs. The d-Nav® insulin management program was developed by two University of Michigan researchers and has been peer-reviewed with studies published in leading medical journals. Hygieia is headquartered in Livonia, Michigan. Learn more at hygieia.com.

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Debbie Reinheimer
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