Kyowa Hakko's Setria® is the No. 1 Selling Brand of Glutathione

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Kyowa Hakko USA’s “Master Antioxidant” tops SPINS natural products supermarkets list *

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Setria® Glutathione is the No. 1 selling brand of glutathione in natural product supermarkets, according to SPINS, an industry source of health and wellness retail data and intelligence. The rating was for the 52 weeks ending Sept. 9, 2018.

Setria® is a clinically studied and patented glutathione manufactured by Kyowa Hakko Bio Co., Ltd. Its uses span immune support, skin health, detoxification support, and free radical support. More than 50 brands incorporate Setria® into dietary supplements.*

Glutathione — found in virtually every cell of the human body and known as the master antioxidant — is well-known for protecting cells from oxidative stress and toxins. Clinical studies show Setria® is absorbed by the body and that daily supplementation increases reduced glutathione levels in the blood making glutathione available for its supportive properties.1

Setria® plays a key role in protecting all kinds of cells from the damaging effects of ingested chemicals and potential carcinogens the body has already absorbed. It also assists in protein synthesis, DNA repair, enzyme function, transport, and cell maturation. Higher levels of glutathione also are associated with optimal physical and mental health. *

“The list of benefits glutathione provides our bodies is almost endless,” said Danielle Citrolo, PharmD, scientific and regulatory affairs manager, Kyowa Hakko USA. “We’re honored that consumers view Setria® as the go-to brand for supporting their health.”

Setria® is made via a patented, proprietary fermentation process that results in a form of glutathione that:

  • Boosts the body’s natural defense system*
  • Helps your body fight oxidative stress*
  • Promotes healthy aging and overall health*
  • Replenishes your body’s primary defense system*
  • Supports immune health*
  • Supports liver health by eliminating harmful toxins*

The loss of glutathione stores due to aging lowers the body’s defenses to harmful effects of sunlight and toxins. Setria® has been shown to help reduce wrinkles and support skin brightening. In addition, some consumers use glutathione as a skin brightener to lower melanin levels, which also helps fade aging spots.2 *

For more information about Setria® Glutathione, visit
About Setria

Setria® Glutathione, manufactured by Kyowa Hakko Bio Co., Ltd., is a clinically studied and patented form of glutathione that, when taken orally1, has been shown to replenish the body's reserves, which may be depleted as a result of poor lifestyle choices, stress or natural aging. Called the "master antioxidant," glutathione helps protect cells in the body from the damaging effects of oxidative stress and toxins. Setria® Glutathione is manufactured through a patented fermentation process to yield high purity and high quality, is non-GMO, vegetarian and allergen-free. For more information about Setria® Glutathione, visit
1 Richie JP Jr, Nichenametla S, Neidig W, Calcagnotto A, Haley JS, Schell TD, Muscat JE. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. European Journal of Nutrition. May 2014: 1436-6207. doi: 10.1007/s00394-014-0706-z
2 Weschawalit S, Thongthip S, Phutrakool P, Asawanonda P. Glutathione and its antiaging and antimelanogenic effects. Dove Press. 27 April 2017 Volume 2017:10 Pages 147—153. Doi:
3 McKinley S, Andrew T, Morita M, Willoughby D. Combined L-Citrulline and Glutathione Supplementation Increases the Concentration of Markers Indicative of Nitric Oxide Synthesis. Journal of the International Society of Sports Nutrition. 2015, 12:27

About Kyowa Hakko USA
Kyowa Hakko USA is the North & South American office for Kyowa Hakko Bio Co. Ltd., an international health ingredients manufacturer and world leader in the development, manufacturing, and marketing of pharmaceuticals, nutraceuticals and food products. Kyowa is the maker of branded ingredients including Cognizin® Citicoline, Pantesin® Pantethine, Setria® Glutathione, as well as Sustamine® L-Alanyl-L-Glutamine. For more information visit

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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Elyse Lovett
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