Max Lugavere Podcast: Kyowa Expert Outlines the Importance of Science When Choosing Supplements *

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Danielle Citrolo, PharmD shows how to spot quality ingredients, trusted products *

Choosing the right dietary supplements is hard. Store shelves are packed with options for everything from brain health to cholesterol control to workout enhancement. So how do you make the best choices?

Danielle Citrolo, PharmD, Registered Pharmacist Scientific & Regulatory Affairs Manager, Kyowa Hakko USA, recommends consumers follow the science. In an interview on “The Genius Life” podcast with health science journalist Max Lugavere, Dr. Citrolo explains there are myriad resources to analyze dietary supplement ingredients.

“Generally, people who take supplement do their research…and they should,” Dr. Citrolo said. One online resource, PubMed, offers a library of validated clinical and scientific studies. But such research can be difficult for general consumers to understand. *

“That’s why you should check the label and contact the supplement maker for more information," she said. “Manufacturers should be helping consumers understand the ingredients in their products.” With a branded ingredient like Cognizin® Citicoline," she added, "Kyowa Hakko provides a wealth of educational materials on its website." *

Branded ingredients tend to undergo more rigorous clinical research. For example, studies done on Cognizin® follow a “gold standard” protocol where the ingredient is tested against a placebo and taken by a “blinded” group of subjects…meaning researchers don’t know the identity of any one individual. *

That process has worked well for Cognizin®. Lugavere said he’s “picky about the brands he works with.” He’s dedicated to educating people about brain health and the use of citicoline is a key part of that. “When you take citicoline, you’re guaranteeing that it ends up in your brain cells,” he said. How? Citicoline crosses the blood-brain barrier in ways other nutrients don’t. It’s critical for softer, suppler brain cell membranes, which allow for better nutrient absorption and faster connections to other part of the body. *

“It’s like electricity going through wires,” Dr. Citrolo said. “Healthy cell membranes allow for quicker connections in your brain. Our cell membranes get more rigid as we age, much like other body parts. Citicoline helps with regeneration of phospholipids that soften cell membranes. Quicker connections result, which can lead to better health.” *

“The Genius Life” podcast with Dr. Citrolo is available on Lugavere’s website on Dec. 12. The full interview can be found at:

The duo also discuss Kyowa’s patented fermentation process and the creation of other amino acid ingredients such as Setria® L-Glutathione and Sustamine® L-Alanyl-L-Glutamine.

About Max Lugavere
Ever since his mom was diagnosed with dementia, Max has made it his life goal to educate people about brain health— from foods and supplements — everyday ways to a healthier relationship with your brain. A filmmaker, TV personality and health and science journalist, Max is the NYTimes best-selling of Genius Foods. He lives in New York City and Los Angeles. For more information, visit

About Danielle Citrolo
Danielle Citrolo is the PharmD, Technical Services Manager for Kyowa Hakko USA. Dr. Citrolo provides technical and regulatory support to Kyowa customers in the U.S., Canada, and Latin America. She holds degrees in biochemistry and chemistry from North Carolina State University and a Doctor of Pharmacy from Albany College of Pharmacy.

About Cognizin
Cognizin® Citicoline, manufactured by Kyowa Hakko Bio Co., Ltd., is a clinically studied and patented form of Citicoline, a natural substance found in every cell of the body and especially vital to brain health.* Citicoline is a potent brain-health nutrient. A proprietary form of citicoline, Cognizin® has been clinically studied to support mental energy, focus, attention, and recall. Cognizin is manufactured through a patented fermentation process to yield high quality and high purity. Cognizin is also highly stable, GRAS, pure and allergen-free. For more information on Cognizin, visit

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