Neuroimaging in Parkinson’s Disease, Upcoming Webinar Hosted by Xtalks

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In this free webinar, the featured speaker will explore neurobiology of Parkinson’s Disease (PD) and DaTscan SPECT in the differential diagnosis of movement disorders. Attendees will learn about Volumetric MRI and Diffusion Tensor Imaging analytic techniques and how neuroimaging can enrich a clinical trial population.

Xtalks Life Science Webinars

The webinar will present findings from the open source Parkinson’s Progression Markers Initiative database, which suggests that baseline volumetric MRI and diffusion tensor imaging (DTI) can meaningfully inform the longitudinal progression of DaTscan uptake in PD patients.

Join David Scott, PhD, Scientific Director, Bioclinica in a live webinar on Tuesday, May 12, 2020 at 10:30am EDT (3:30pm BST/UK).

Nigrostriatal dopaminergic denervation is a critical pathological event in Parkinson’s Disease (PD) and related disorders. Degeneration of presynaptic neurons leads to reduced density of dopamine transporters in the striatum, the progression of which leads to development of motor deficits and other clinical features.

DaTscan SPECT permits the in vivo assessment of striatal dopamine transporter (DAT) availability, which is the most widely utilized imaging biomarker for clinical trials in PD. Emerging evidence suggests that a pattern of reduced volume in the striatum and altered morphometry throughout the brain may inform the likelihood of progressive reduction in DaTscan binding.

In this webinar, the speaker will discuss how the integration of biomarkers across neuroimaging modalities can improve the characterization of PD disease state and help to predict whether a PD patient will reliably progress over the time frame of a clinical trial.

The webinar will present findings from the open source Parkinson’s Progression Markers Initiative database, which suggests that baseline volumetric MRI and diffusion tensor imaging (DTI) can meaningfully inform the longitudinal progression of DaTscan uptake in PD patients. It will also explore the performance of different image processing pipelines, analytic endpoints and anatomic localization to determine which combination is most sensitive in predicting disease progression.

For more information or to register for this event, visit Neuroimaging in Parkinson’s Disease.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com
For information about hosting a webinar visit http://xtalks.com/why-host-a-webinar/

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Sydney Perelmutter
Xtalks
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