In this free webinar, learn about how measuring titer using instruments specifically designed for cell line development applications and workflow differ from common methods. Attendees will see data from customer use cases that demonstrate how clone selection based on titer alone missed the highest performers. The featured speakers will discuss how combined titer and confluence measurements from the cloning plate helped predict which clones perform best in shake flasks. The speakers will evaluate opportunities to accelerate cell line development process timelines by leveraging early data points in the decision-making.
TORONTO, May 16, 2023 /PRNewswire-PRWeb/ -- In cell line development today, the pressure to make decisions on best-performing clones earlier and shorten timelines continues to grow. One factor in the decision-making process is a cell line's productivity, necessitating the measurement of titer.
Currently, titer measurements in cell line development are mostly performed using incumbent methods such as Octet and ELISA, which have their strengths but were not specifically developed for cell line development applications. The minimum sample volume requirements of these methods mean that titer measurements have often been neglected at the earlier cloning plate stage when 96 and 384 well plates are being used. Alternatively, samples have been diluted, leading to additional liquid handling steps and possible errors.
During this webinar, attendees will see featured case studies from users of the Solentim ICON, an instrument that was specifically designed to meet the demands of the cell line development workflow. ICON technology uses lower sample volumes for titer and viable cell density (VCD) measurements in higher density formats such as 384, 96 and 24 well plates. The case studies also show how faster titer measurements helped to allow clones to be excluded more rapidly, enabling decision-making earlier and shortening the cell line development process by days to weeks.
The user case studies also show how combining titer and confluence measurements from cell populations in the cloning plate gives a valuable new perspective regarding which clones turn out to perform best in shake flasks.
Join this webinar to see how to accelerate cell line development process timelines by leveraging early data points in the decision-making.
Join Kayla Bean, Principal Scientist, Cell Line Development, ACG Biologics; Paul Butler, Senior Product Leader, Advanced Instruments, LLC.; and Jenica Lee, Senior Research Associate, Wheeler Bio, for the live webinar on Tuesday, June 6, 2023, at 11am EDT (4pm BST/UK).
For more information, or to register for this event, visit Optimal Cell Line Development: Save Weeks AND Don't Reject Your Highest Performing Clones.
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