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The Allograft Provides the Greatest Guided-Bone Regeneration Potential


News provided by

Journal of Oral Implantology

Mar 15, 2023, 11:00 ET

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Issue 48 Volume 6
Issue 48 Volume 6

In this retrospective review, published in the Journal of Oral Implantology, researchers aimed to compare three types of bone grafts to support successful GBR, including allograft, xenograft, and alloplast.

LAWRENCE, Kan., March 15, 2023 /PRNewswire-PRWeb/ -- Journal of Oral Implantology – Tooth extractions can be necessary for proper dental care and increasing the longevity of oral health. Though tooth extractions are one of the most performed surgeries in dentistry, they can cause problems maintaining the mouth's structure and preserving the jawbone. To ensure minimal impact from tooth extraction, dental professionals often recommend guided-bone regeneration (GBR) after extraction to help regenerate supportive bone for optimal oral health.

"Considering the dimensional changes to the bone region, following tooth extraction, alveolar ridge preservation via [GBR] can be strategically included in the treatment plan," pens Eirini Zampara, DMD, and colleagues from a multinational study group from the United States, Brazil, and Greece. Zampara et al. recently published a retrospective review in the Journal of Oral Implantology to compare three types of bone grafts to support successful GBR, including allograft, xenograft, and alloplast. The study results ultimately show that the allograft provides the greatest GBR potential for successful healing subsequent to necessary tooth extraction procedures. Zampara et al conclude that "[d]epending on the type of the defect, the operative site, and the esthetic requirements, each bone substitute can be used if properly adapted with a treatment plan." They go on to suggest that "[f]urther studies, with a greater number and more homogenous group of samples, should be conducted to validate these findings and shed light to the concept of ridge preservation."

Considering the dimensional changes to the bone region, following tooth extraction, alveolar ridge preservation via [GBR] can be strategically included in the treatment plan

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A total of 32 participants, 19 men and 13 women aged 45 to 70 years needing tooth extraction, were enrolled in this randomized control, multiarm trial. Equal representation of the maxilla and mandible (n =16) was included. Each graft type was assessed through the following qualitative and quantitative variables: (i) graft particle present over time; (ii) structured bone density; (iii) osteoblastic and osteoclastic cell presence and activity level; and (iv) angiogenic activity around the bone regeneration site.

Zampara and colleagues observed that the alloplast group showed the highest vital bone percentage with the lowest residual graft particles. No significant differences in newly formed bone or percentage of residual graft particles were seen between the alloplast, allograft, or control groups. The xenograft presented the lowest amount of regenerated bone and the highest percentage of residual graft particles. All three graft materials resulted in effective alveolar ridge preservation as all surgeries were performed as planned, and none of the participants reported complications during the observed healing period.

The study results ultimately show that the allograft provides the greatest GBR potential for successful healing subsequent to necessary tooth extraction procedures. Zampara et al conclude that "[d]epending on the type of the defect, the operative site, and the esthetic requirements, each bone substitute can be used if properly adapted with a treatment plan." They continue that "[f]urther studies, with a greater number and more homogenous group of samples, should be conducted to validate these findings and shed light to the concept of ridge preservation."

Full text of the article, "A Histologic and Histomorphometric Evaluation of an Allograft, Xenograft, and Alloplast Graft for Alveolar Ridge Preservation in Humans: A Randomized Controlled Clinical Trial" Journal of Oral Implantology, Vol. 48, No. 6, 2022, is available at https://doi.org/10.1563/aaid-joi-D-21-00012

###

About the Journal of Oral Implantology
The Journal of Oral Implantology is the official publication of the American Academy of Implant Dentistry and of the American Academy of Implant Prosthodontics. It is dedicated to providing valuable information to general dentists, oral surgeons, prosthodontists, periodontists, scientists, clinicians, laboratory owners and technicians, manufacturers, and educators. The JOI distinguishes itself as the first and oldest journal in the world devoted exclusively to implant dentistry. For more information about the journal or society, please visit http://www.joionline.org.

###

Media Contact:
Samantha Weinkauf
KnowledgeWorks Global Ltd
785/865-9123
[email protected]

Media Contact

Samantha, KnowledgeWorks Global Ltd., 1 785-865-9123, [email protected]

SOURCE Journal of Oral Implantology

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