The Evolving Role of Ion Channels in Shaping Successful Drug Discovery, Upcoming Webinar Hosted by Xtalks

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In this free webinar, attendees will learn about the importance of ion channels in drug discovery and how this is evolving. The featured speaker will discuss advances in ion channel biology, experimental technologies and in vitro models, new ion channel ligands and toxicological considerations.

Targeting ion channels selectively has always been challenging. New, more specific modalities including antibodies, aptamers, peptides and knotbodies are also being explored.

There are over 200 ion channels in the human body, all playing a pivotal role in normal physiology. As such, they are important targets for drug therapies that modulate ion channels in critical pathways, or correct aberrant ion channel function. To date, there are over 150 marketed drugs that target ion channels. Many of these drugs are anaesthetics, anti-epileptics or are active in the cardiovascular system.

The importance of ion channels in the pharmaceutical industry is evolving. As knowledge of ion channel physiology and how to target ion channels evolves, therapeutic opportunities are becoming more diverse, extending to renal and respiratory disease, inflammation, cancer, pain and depression. How the pharmaceutical industry tests and explores ion channels is also evolving with high-throughput platforms and hiPSC models.

Targeting ion channels selectively has always been challenging. New, more specific modalities including antibodies, aptamers, peptides and knotbodies are also being explored. Finally, given the importance of ion channels in normal physiology, unwanted activity at ion channels in the heart or CNS can cause serious adverse effects and should be avoided. In this respect, screening for effects on ion channels is a key, rapidly developing area of drug discovery.

Consideration of these evolving areas in ion channel drug discovery is critical to the successful development of new medicines.

Join Dr. Michael Morton, Director, ApconiX Ltd in a live webinar on Thursday, November 19, 2020 at 11am EST (4pm GMT/UK).

For more information, or to register for this event, visit The Evolving Role of Ion Channels in Shaping Successful Drug Discovery.

ABOUT XTALKS

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global life science, food and medical device community. Every year, thousands of industry practitioners (from life science, food and medical device companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com
For information about hosting a webinar visit http://xtalks.com/why-host-a-webinar/

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Sydney Perelmutter
Xtalks
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