The goal of this webinar will be to provide an understanding of laboratory animal diet composition and the influence of diet divergence on shifts in the gut microbiota.
TORONTO (PRWEB) June 26, 2020
The gut microbiota can influence metabolic health, behavior, and disease state. Microbial communities in laboratory rodents are relatively stable but can be influenced by environmental factors such as diet. The extent to which diet influences the microbiota is dependent on nutrient levels, ingredient composition, and non-nutrients.
Diet composition can profoundly influence study outcomes and the interpretation of microbiota data in rodents. Dietary ingredients can range from natural ingredients (corn, wheat, etc.) which contain multiple nutrient classes to highly refined ingredients (casein, corn starch, sucrose, etc.) that allow for the precise control of nutrient levels and limit non-nutritive factors.
A basic knowledge of diet composition is key to understanding the potential microbiota shifts associated with diet divergence. Standard natural ingredient diets or “chows” are fed to maintain animal colonies and at times are fed as control diets. These diets are primarily grain-based and therefore contain high levels of complex plant polysaccharides and diverse fiber sources. Purified diets utilize refined ingredients that are more readily digested and absorbed, are relatively low in total fiber compared to standard diets, and typically lack fermentable fibers. Studies where purified diets are compared to natural ingredient control diets may inappropriately attribute microbiota shifts to a single dietary component rather than changes in dietary pattern.
The goal of this webinar will be to provide an understanding of laboratory animal diet composition and the influence of diet divergence on shifts in the gut microbiota. Join Tina Herfel, PhD, Nutritionist, Teklad Diets at Envigo in the live session on Wednesday, July 15, 2020 at 11am EDT (4pm BST/UK).
For more information or to register for this event, visit The Role of the Laboratory Animal Diet in Shaping the Gut Microbiota.
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