Accessibility Statement Skip Navigation
  • Why PRWeb
  • How It Works
  • Who Uses It
  • Pricing
  • Login
  • GDPR
  • Create a Free Account
Return to PRWeb homepage
  • News
  • Resources
  • Contact
When typing in this field, a list of search results will appear and be automatically updated as you type.

Searching for your content...

No results found. Please change your search terms and try again.
  • News in Focus
      • Browse News Releases

      • All News Releases
      • Multimedia Gallery

      • All Multimedia
      • All Photos
      • All Videos
  • Business & Money
      • Auto & Transportation

      • Aerospace, Defense
      • Air Freight
      • Airlines & Aviation
      • Automotive
      • Maritime & Shipbuilding
      • Railroads and Intermodal Transportation
      • Supply Chain/Logistics
      • Transportation, Trucking & Railroad
      • Travel
      • Trucking and Road Transportation
      • View All Auto & Transportation

      • Business Technology

      • Blockchain
      • Broadcast Tech
      • Computer & Electronics
      • Computer Hardware
      • Computer Software
      • Data Analytics
      • Electronic Commerce
      • Electronic Components
      • Electronic Design Automation
      • Financial Technology
      • High Tech Security
      • Internet Technology
      • Nanotechnology
      • Networks
      • Peripherals
      • Semiconductors
      • View All Business Technology

      • Entertain­ment & Media

      • Advertising
      • Art
      • Books
      • Entertainment
      • Film and Motion Picture
      • Magazines
      • Music
      • Publishing & Information Services
      • Radio & Podcast
      • Television
      • View All Entertain­ment & Media

      • Financial Services & Investing

      • Accounting News & Issues
      • Acquisitions, Mergers and Takeovers
      • Banking & Financial Services
      • Bankruptcy
      • Bond & Stock Ratings
      • Conference Call Announcements
      • Contracts
      • Cryptocurrency
      • Dividends
      • Earnings
      • Earnings Forecasts & Projections
      • Financing Agreements
      • Insurance
      • Investments Opinions
      • Joint Ventures
      • Mutual Funds
      • Private Placement
      • Real Estate
      • Restructuring & Recapitalization
      • Sales Reports
      • Shareholder Activism
      • Shareholder Meetings
      • Stock Offering
      • Stock Split
      • Venture Capital
      • View All Financial Services & Investing

      • General Business

      • Awards
      • Commercial Real Estate
      • Corporate Expansion
      • Earnings
      • Environmental, Social and Governance (ESG)
      • Human Resource & Workforce Management
      • Licensing
      • New Products & Services
      • Obituaries
      • Outsourcing Businesses
      • Overseas Real Estate (non-US)
      • Personnel Announcements
      • Real Estate Transactions
      • Residential Real Estate
      • Small Business Services
      • Socially Responsible Investing
      • Surveys, Polls and Research
      • Trade Show News
      • View All General Business

  • Science & Tech
      • Consumer Technology

      • Artificial Intelligence
      • Blockchain
      • Cloud Computing/Internet of Things
      • Computer Electronics
      • Computer Hardware
      • Computer Software
      • Consumer Electronics
      • Cryptocurrency
      • Data Analytics
      • Electronic Commerce
      • Electronic Gaming
      • Financial Technology
      • Mobile Entertainment
      • Multimedia & Internet
      • Peripherals
      • Social Media
      • STEM (Science, Tech, Engineering, Math)
      • Supply Chain/Logistics
      • Wireless Communications
      • View All Consumer Technology

      • Energy & Natural Resources

      • Alternative Energies
      • Chemical
      • Electrical Utilities
      • Gas
      • General Manufacturing
      • Mining
      • Mining & Metals
      • Oil & Energy
      • Oil and Gas Discoveries
      • Utilities
      • Water Utilities
      • View All Energy & Natural Resources

      • Environ­ment

      • Conservation & Recycling
      • Environmental Issues
      • Environmental Policy
      • Environmental Products & Services
      • Green Technology
      • Natural Disasters
      • View All Environ­ment

      • Heavy Industry & Manufacturing

      • Aerospace & Defense
      • Agriculture
      • Chemical
      • Construction & Building
      • General Manufacturing
      • HVAC (Heating, Ventilation and Air-Conditioning)
      • Machinery
      • Machine Tools, Metalworking and Metallurgy
      • Mining
      • Mining & Metals
      • Paper, Forest Products & Containers
      • Precious Metals
      • Textiles
      • Tobacco
      • View All Heavy Industry & Manufacturing

      • Telecomm­unications

      • Carriers and Services
      • Mobile Entertainment
      • Networks
      • Peripherals
      • Telecommunications Equipment
      • Telecommunications Industry
      • VoIP (Voice over Internet Protocol)
      • Wireless Communications
      • View All Telecomm­unications

  • Lifestyle & Health
      • Consumer Products & Retail

      • Animals & Pets
      • Beers, Wines and Spirits
      • Beverages
      • Bridal Services
      • Cannabis
      • Cosmetics and Personal Care
      • Fashion
      • Food & Beverages
      • Furniture and Furnishings
      • Home Improvement
      • Household, Consumer & Cosmetics
      • Household Products
      • Jewelry
      • Non-Alcoholic Beverages
      • Office Products
      • Organic Food
      • Product Recalls
      • Restaurants
      • Retail
      • Supermarkets
      • Toys
      • View All Consumer Products & Retail

      • Entertain­ment & Media

      • Advertising
      • Art
      • Books
      • Entertainment
      • Film and Motion Picture
      • Magazines
      • Music
      • Publishing & Information Services
      • Radio & Podcast
      • Television
      • View All Entertain­ment & Media

      • Health

      • Biometrics
      • Biotechnology
      • Clinical Trials & Medical Discoveries
      • Dentistry
      • FDA Approval
      • Fitness/Wellness
      • Health Care & Hospitals
      • Health Insurance
      • Infection Control
      • International Medical Approval
      • Medical Equipment
      • Medical Pharmaceuticals
      • Mental Health
      • Pharmaceuticals
      • Supplementary Medicine
      • View All Health

      • Sports

      • General Sports
      • Outdoors, Camping & Hiking
      • Sporting Events
      • Sports Equipment & Accessories
      • View All Sports

      • Travel

      • Amusement Parks and Tourist Attractions
      • Gambling & Casinos
      • Hotels and Resorts
      • Leisure & Tourism
      • Outdoors, Camping & Hiking
      • Passenger Aviation
      • Travel Industry
      • View All Travel

  • Policy & Public Interest
      • Policy & Public Interest

      • Advocacy Group Opinion
      • Animal Welfare
      • Congressional & Presidential Campaigns
      • Corporate Social Responsibility
      • Domestic Policy
      • Economic News, Trends, Analysis
      • Education
      • Environmental
      • European Government
      • FDA Approval
      • Federal and State Legislation
      • Federal Executive Branch & Agency
      • Foreign Policy & International Affairs
      • Homeland Security
      • Labor & Union
      • Legal Issues
      • Natural Disasters
      • Not For Profit
      • Patent Law
      • Public Safety
      • Trade Policy
      • U.S. State Policy
      • View All Policy & Public Interest

  • People & Culture
      • People & Culture

      • Aboriginal, First Nations & Native American
      • African American
      • Asian American
      • Children
      • Diversity, Equity & Inclusion
      • Hispanic
      • Lesbian, Gay & Bisexual
      • Men's Interest
      • People with Disabilities
      • Religion
      • Senior Citizens
      • Veterans
      • Women
      • View All People & Culture

  • Hamburger menu
  • Cision PRWeb provides efficient communication tools to continuously engage with target audiences across multiple online channels
  • Create a Free Account
    • ALL CONTACT INFO
    • Contact Us


      11AM ET Sunday – 8PM ET Friday

  • Send a Release
  • Sign up
  • Log in
  • Resources
  • RSS
  • GDPR
  • News in Focus
    • Browse All News
    • Multimedia Gallery
  • Business & Money
    • Auto & Transportation
    • Business Technology
    • Entertain­ment & Media
    • Financial Services & Investing
    • General Business
  • Science & Tech
    • Consumer Technology
    • Energy & Natural Resources
    • Environ­ment
    • Heavy Industry & Manufacturing
    • Telecomm­unications
  • Lifestyle & Health
    • Consumer Products & Retail
    • Entertain­ment & Media
    • Health
    • Sports
    • Travel
  • Policy & Public Interest
  • People & Culture
    • People & Culture
  • Send a Release
  • Sign up
  • Log in
  • Resources
  • RSS
  • GDPR
  • Send a Release
  • Sign up
  • Log in
  • Resources
  • RSS
  • GDPR
  • Send a Release
  • Sign up
  • Log in
  • Resources
  • RSS
  • GDPR

Lycotec Patented First Nutra-Pharmaceutical Drug to Treat Infection Behind Cardiovascular Disease
  • USA - English


News provided by

Lycotec Ltd.

Jan 30, 2017, 03:00 ET

Share this article

Share toX

Share this article

Share toX


Cambridge UK (PRWEB UK) 30 January 2017 -- Lycotec Ltd., a biotech company based in Cambridge UK, http://www.lycotec.com has filed a patent application for the first drug in the treatment of a bacterial infection which could be involved in the development of atherosclerosis and cardiovascular disease, CVD.

First nutra-pharmaceutical drug to treat infection behind cardiovascular disease.

Post this

An infection as a cause of cardiovascular pathology has been sought for more than 100 years. In the last 20-25 years a number of bacteria and viruses have been identified in atherosclerotic plaques of people with CVD. One of the most reported findings was a detection of fragments, DNA and antibodies against Chlamydia pneumoniae, Ch. pn., the most common respiratory infection in humans.

A strong correlation has been established between the presence of signs of the infection and the severity of atherosclerosis and CVD. However, to prove that Ch. pn., is indeed a causative factor of this disease, it was necessary to demonstrate that anti-Chlamydia treatment could alleviate symptoms of cardiovascular pathology.

Numerous trials on the application of different antibiotics in patients with CVD have so far failed to achieve this.

Analysis of these unsuccessful attempts reveals two major flaws in their design. Firstly, in none of these trials was a monitoring of the elimination of Ch. pn. applied, hence there was no evidence that antibiotics used in these patients were effective in inhibiting the infection.

Secondly, protocols of the administration of these drugs were the same as used for the treatment of acute Chlamydia infection.

However, the majority of the CVD patients enrolled in these studies did not have concomitant respiratory diseases. In these patients Ch. pn. was typically present in its persistent chronic form, which can be either resistant to existing antibiotics, or require longer treatment than the acute infection.

Lycotec has developed the first drug to target the particular persistent form of Chlamydia. It blocks intra-cellular propagation of these bacteria in cell cultures. In a number of clinical studies, including randomised, double blind and placebo controlled ones, on patients with diagnosed CVD, it was demonstrated that oral administration of this drug for four weeks could in 85% patients not only reduce anti-chlamydia antibodies but also blood markers of oxidative inflammatory damage to an undetectable level.

The drug and results of its clinical trials are to be presented at the biennial CBRS Conference in Charlotte, NC, in April 2017 http://www.chlamydiabasicresearchsociety.org/biennial-meeting.html

The drug belongs to a class of Nutra-Pharmaceuticals because its active molecule, lycopene, and its two “assisting” molecules originate from food. For example, lycopene is a red pigment of tomatoes, and some other red fruits. All the molecules can be either extracted from food or synthetized.

In its conventional form lycopene itself cannot inhibit chlamydia. It needs a chaperon, which is essential to facilitate lycopene transportation to the site of the infection. Moreover, if the infective process is accompanied by a pronounced inflammatory reaction, it is important to have in the drug formulation a co-factor which prolongs the life of lycopene, protecting it from oxidation and depletion.
Since all three molecules comprising the drug are of food origin, it is intrinsically safe due to the absence of any toxicity issue.

All the active molecules are typically present in the Mediterranean diet, which has a well-established association with reduced prevalence of and mortality from CVD.

Dr Ivan Petyaev, one of the inventors, and the founder of Lycotec, suggests that the development of the anti-chlamydia Nutra-Pharmaceutical and the demonstration of its efficacy in clinic may provide one of the explanations of how the Mediterranean diet can provide cardiovascular support and protection.

Professor Nailya Zigangirova, the co-author of the invention, points out additional new applications of the drug in the treatment of other chlamydia infections, including Chlamydia trachomatis, one of the most common sexually transmitted diseases. Although its acute symptomatic form can be cured by existing antibiotics, its persistent asymptomatic form is still poorly treated. This in turn becomes one of the leading causes of infertility.

Lycotec is currently looking for funding, or a licensing and partnering deal with a Pharma company, to take its new patented drug for further clinical trials and regulatory approval.

For more information please contact info(at)lycotec(dot)com

Ivan Petyaev, Lycotec Ltd., http://www.lycotec.com, +44 7921363740, [email protected]

Modal title

Chlamydia trachomatis Inhibition
View PDF
Chlamydia trachomatis Inhibition
Chlamydia pneumoniae Inhibition
View PDF
Chlamydia pneumoniae Inhibition
Chlamydia trachomatis Inhibition Chlamydia pneumoniae Inhibition

Contact PRWeb

  • 11AM ET Sunday – 8PM ET Friday
  • Contact Us

About PRWeb

  • About PRWeb
  • Partners
  • Partnership Programs
  • Editorial Guidelines
  • Resources

Why PRWeb

  • Why PRWeb
  • How It Works
  • Who Uses It
  • Pricing

Accounts

  • Create a Free Account
  • Log in
  • Contact Us

Do not sell or share my personal information:

  • Submit via [email protected] 
  • Call Privacy toll-free: 877-297-8921

Contact Cision

Products

About

My Services
  • All News Releases
  • Online Member Center
  • ProfNet
Cision Distribution Helpline
888-776-0942
  • Legal
  • Site Map
  • RSS
  • Cookie Settings
Copyright © 2025 Cision US Inc.